Effects of gelam (Melaleuca sp.) honey on apoptosis pathway of colorectal cancer cell lines (HCT116) / Nurul Farah Hana Mohd Adnan
Honey is reported to contain various compounds such as phenols, vitamins and antioxidants. The present study investigates the anticancer potential of Gelam honey in colorectal cancer cell lines (HCT116). The cells were treated with decreasing doses of Gelam honey (10-0.01%) for 72 hours. The activat...
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my-uitm-ir.668012022-09-15T06:29:18Z Effects of gelam (Melaleuca sp.) honey on apoptosis pathway of colorectal cancer cell lines (HCT116) / Nurul Farah Hana Mohd Adnan 2012 Mohd Adnan, Nurul Farah Hana Cytology Research. Experimentation Honey is reported to contain various compounds such as phenols, vitamins and antioxidants. The present study investigates the anticancer potential of Gelam honey in colorectal cancer cell lines (HCT116). The cells were treated with decreasing doses of Gelam honey (10-0.01%) for 72 hours. The activation of caspase-3 and -9 were observed in all-Gelam honey-treated cancer cells indicating the involvement of mitochondrial apoptotic pathway. This study shows that Gelam honey has significant anticancer activity against colorectal cancer cell lines. 2012 Thesis https://ir.uitm.edu.my/id/eprint/66801/ https://ir.uitm.edu.my/id/eprint/66801/1/66801.pdf text en public degree Universiti Teknologi MARA (UiTM) Faculty of Pharmacy Wan Ismail, Wan Iryani |
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Universiti Teknologi MARA |
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UiTM Institutional Repository |
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English |
advisor |
Wan Ismail, Wan Iryani |
topic |
Cytology Cytology |
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Cytology Cytology Mohd Adnan, Nurul Farah Hana Effects of gelam (Melaleuca sp.) honey on apoptosis pathway of colorectal cancer cell lines (HCT116) / Nurul Farah Hana Mohd Adnan |
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Honey is reported to contain various compounds such as phenols, vitamins and antioxidants. The present study investigates the anticancer potential of Gelam honey in colorectal cancer cell lines (HCT116). The cells were treated with decreasing doses of Gelam honey (10-0.01%) for 72 hours. The activation of caspase-3 and -9 were observed in all-Gelam honey-treated cancer cells indicating the involvement of mitochondrial apoptotic pathway. This study shows that Gelam honey has significant anticancer activity against colorectal cancer cell lines. |
format |
Thesis |
qualification_level |
Bachelor degree |
author |
Mohd Adnan, Nurul Farah Hana |
author_facet |
Mohd Adnan, Nurul Farah Hana |
author_sort |
Mohd Adnan, Nurul Farah Hana |
title |
Effects of gelam (Melaleuca sp.) honey on apoptosis pathway of colorectal cancer cell lines (HCT116) / Nurul Farah Hana Mohd Adnan |
title_short |
Effects of gelam (Melaleuca sp.) honey on apoptosis pathway of colorectal cancer cell lines (HCT116) / Nurul Farah Hana Mohd Adnan |
title_full |
Effects of gelam (Melaleuca sp.) honey on apoptosis pathway of colorectal cancer cell lines (HCT116) / Nurul Farah Hana Mohd Adnan |
title_fullStr |
Effects of gelam (Melaleuca sp.) honey on apoptosis pathway of colorectal cancer cell lines (HCT116) / Nurul Farah Hana Mohd Adnan |
title_full_unstemmed |
Effects of gelam (Melaleuca sp.) honey on apoptosis pathway of colorectal cancer cell lines (HCT116) / Nurul Farah Hana Mohd Adnan |
title_sort |
effects of gelam (melaleuca sp.) honey on apoptosis pathway of colorectal cancer cell lines (hct116) / nurul farah hana mohd adnan |
granting_institution |
Universiti Teknologi MARA (UiTM) |
granting_department |
Faculty of Pharmacy |
publishDate |
2012 |
url |
https://ir.uitm.edu.my/id/eprint/66801/1/66801.pdf |
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1783735640559452160 |