Light microscopic study of hepato-renal lesion & their reversibility after long term administration of arsenic trioxide in Sprague Dawley rats / Siti Sarah Ahmad Shahidan

Light microscopic study of hepato-renal lesion & their reversibility after long term administration of arsenic trioxide in Sprague Dawley rats / Siti Sarah Ahmad Shahidan

Background: Arsenic is widely distributed in nature in the form of chemical compound or metalloids. It is found to be mixed with drinking water of shallow natural reservoirs. Over 100 million people of the world are at risk of exposure to arsenic. It causes variety of pathologic conditions including...

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Main Author: Ahmad Shahidan, Siti Sarah
Format: Thesis
Language:English
Published: 2013
Subjects:
QL Zoology
QM Human anatomy
Online Access:https://ir.uitm.edu.my/id/eprint/72158/1/72158.pdf
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spelling my-uitm-ir.721582024-01-04T09:59:21Z Light microscopic study of hepato-renal lesion & their reversibility after long term administration of arsenic trioxide in Sprague Dawley rats / Siti Sarah Ahmad Shahidan 2013 Ahmad Shahidan, Siti Sarah QL Zoology QM Human anatomy Background: Arsenic is widely distributed in nature in the form of chemical compound or metalloids. It is found to be mixed with drinking water of shallow natural reservoirs. Over 100 million people of the world are at risk of exposure to arsenic. It causes variety of pathologic conditions including cutaneous and visceral malignancies. 8-hydroxy-2-deoxyguanosine (8- OHdG) is one of the major reactive oxygen species, widely accepted as a sensitive marker of oxidative DNA damage. The reversibility in organ damage after arsenic exposure is unclear. Objective: To study the histomorphology and 8-OHdG expression in the liver and kidney of rats exposed to long term arsenic and observe its reversibility after arsenic withdrawal. 2013 Thesis https://ir.uitm.edu.my/id/eprint/72158/ https://ir.uitm.edu.my/id/eprint/72158/1/72158.pdf text en public degree Universiti Teknologi MARA (UiTM) Faculty of Medicine Islam, Mohammed Nasimul
institution Universiti Teknologi MARA
collection UiTM Institutional Repository
language English
advisor Islam, Mohammed Nasimul
topic QL Zoology
QM Human anatomy
spellingShingle QL Zoology
QM Human anatomy
Ahmad Shahidan, Siti Sarah
Light microscopic study of hepato-renal lesion & their reversibility after long term administration of arsenic trioxide in Sprague Dawley rats / Siti Sarah Ahmad Shahidan
description Background: Arsenic is widely distributed in nature in the form of chemical compound or metalloids. It is found to be mixed with drinking water of shallow natural reservoirs. Over 100 million people of the world are at risk of exposure to arsenic. It causes variety of pathologic conditions including cutaneous and visceral malignancies. 8-hydroxy-2-deoxyguanosine (8- OHdG) is one of the major reactive oxygen species, widely accepted as a sensitive marker of oxidative DNA damage. The reversibility in organ damage after arsenic exposure is unclear. Objective: To study the histomorphology and 8-OHdG expression in the liver and kidney of rats exposed to long term arsenic and observe its reversibility after arsenic withdrawal.
format Thesis
qualification_level Bachelor degree
author Ahmad Shahidan, Siti Sarah
author_facet Ahmad Shahidan, Siti Sarah
author_sort Ahmad Shahidan, Siti Sarah
title Light microscopic study of hepato-renal lesion & their reversibility after long term administration of arsenic trioxide in Sprague Dawley rats / Siti Sarah Ahmad Shahidan
title_short Light microscopic study of hepato-renal lesion & their reversibility after long term administration of arsenic trioxide in Sprague Dawley rats / Siti Sarah Ahmad Shahidan
title_full Light microscopic study of hepato-renal lesion & their reversibility after long term administration of arsenic trioxide in Sprague Dawley rats / Siti Sarah Ahmad Shahidan
title_fullStr Light microscopic study of hepato-renal lesion & their reversibility after long term administration of arsenic trioxide in Sprague Dawley rats / Siti Sarah Ahmad Shahidan
title_full_unstemmed Light microscopic study of hepato-renal lesion & their reversibility after long term administration of arsenic trioxide in Sprague Dawley rats / Siti Sarah Ahmad Shahidan
title_sort light microscopic study of hepato-renal lesion & their reversibility after long term administration of arsenic trioxide in sprague dawley rats / siti sarah ahmad shahidan
granting_institution Universiti Teknologi MARA (UiTM)
granting_department Faculty of Medicine
publishDate 2013
url https://ir.uitm.edu.my/id/eprint/72158/1/72158.pdf
_version_ 1794191884224036864

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