Mechanism of ocular hypotensive action of angiotensin converting enzyme inhibitor / Raja Nor Intan Safinaz Raja Mat Yassin

Angiotensin converting enzyme inhibitors (ACEIs) have been shown to reduce intraocular pressure (IOP), however, their mechanism of IOP reduction is poorly understood. The possible mechanisms of ACEIs action are include stimulation of the prostaglandin (PG) synthesis leading to increased matrix metal...

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Main Author: Raja Mat Yassin, Raja Nor Intan Safinaz
Format: Thesis
Language:English
Published: 2012
Subjects:
Online Access:https://ir.uitm.edu.my/id/eprint/72169/1/72169.pdf
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spelling my-uitm-ir.721692024-01-02T08:38:21Z Mechanism of ocular hypotensive action of angiotensin converting enzyme inhibitor / Raja Nor Intan Safinaz Raja Mat Yassin 2012 Raja Mat Yassin, Raja Nor Intan Safinaz QP Physiology Angiotensin converting enzyme inhibitors (ACEIs) have been shown to reduce intraocular pressure (IOP), however, their mechanism of IOP reduction is poorly understood. The possible mechanisms of ACEIs action are include stimulation of the prostaglandin (PG) synthesis leading to increased matrix metalloproteinase (MMP) and TNF-alpha activities, as well as reduction of angiotensin II type one receptor activity in the trabecular meshwork. The objective is to evaluate the mechanism of ocular hypotensive action of angiotensin converting enzyme inhibitors. 2012 Thesis https://ir.uitm.edu.my/id/eprint/72169/ https://ir.uitm.edu.my/id/eprint/72169/1/72169.pdf text en public degree Universiti Teknologi MARA (UiTM) Faculty of Medicine Krasilnikova, Anna
institution Universiti Teknologi MARA
collection UiTM Institutional Repository
language English
advisor Krasilnikova, Anna
topic QP Physiology
spellingShingle QP Physiology
Raja Mat Yassin, Raja Nor Intan Safinaz
Mechanism of ocular hypotensive action of angiotensin converting enzyme inhibitor / Raja Nor Intan Safinaz Raja Mat Yassin
description Angiotensin converting enzyme inhibitors (ACEIs) have been shown to reduce intraocular pressure (IOP), however, their mechanism of IOP reduction is poorly understood. The possible mechanisms of ACEIs action are include stimulation of the prostaglandin (PG) synthesis leading to increased matrix metalloproteinase (MMP) and TNF-alpha activities, as well as reduction of angiotensin II type one receptor activity in the trabecular meshwork. The objective is to evaluate the mechanism of ocular hypotensive action of angiotensin converting enzyme inhibitors.
format Thesis
qualification_level Bachelor degree
author Raja Mat Yassin, Raja Nor Intan Safinaz
author_facet Raja Mat Yassin, Raja Nor Intan Safinaz
author_sort Raja Mat Yassin, Raja Nor Intan Safinaz
title Mechanism of ocular hypotensive action of angiotensin converting enzyme inhibitor / Raja Nor Intan Safinaz Raja Mat Yassin
title_short Mechanism of ocular hypotensive action of angiotensin converting enzyme inhibitor / Raja Nor Intan Safinaz Raja Mat Yassin
title_full Mechanism of ocular hypotensive action of angiotensin converting enzyme inhibitor / Raja Nor Intan Safinaz Raja Mat Yassin
title_fullStr Mechanism of ocular hypotensive action of angiotensin converting enzyme inhibitor / Raja Nor Intan Safinaz Raja Mat Yassin
title_full_unstemmed Mechanism of ocular hypotensive action of angiotensin converting enzyme inhibitor / Raja Nor Intan Safinaz Raja Mat Yassin
title_sort mechanism of ocular hypotensive action of angiotensin converting enzyme inhibitor / raja nor intan safinaz raja mat yassin
granting_institution Universiti Teknologi MARA (UiTM)
granting_department Faculty of Medicine
publishDate 2012
url https://ir.uitm.edu.my/id/eprint/72169/1/72169.pdf
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