The effects of bevacizumab on human Tenon’s fibroblasts: an in vitro study / Nurul Nabila Baharudin

Purpose: To understand the effect and mechanism of bevacizumab in inbiting wound healing on primary human Tenon's capsule fibroblasts (HTF) in vitro. Methods: HTF was cultured in RPMI media and bevacizumab was added to study the effect of bevacizumab on HTF in vitro at a concentration of 0.25,1...

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Main Author:	Baharudin, Nurul Nabila
Format:	Thesis
Language:	English
Published:	2013
Subjects:	RM Therapeutics Pharmacology
Online Access:	https://ir.uitm.edu.my/id/eprint/72214/1/72214.pdf
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id	my-uitm-ir.72214
record_format	uketd_dc
spelling	my-uitm-ir.722142024-01-05T03:38:50Z The effects of bevacizumab on human Tenon’s fibroblasts: an in vitro study / Nurul Nabila Baharudin 2013 Baharudin, Nurul Nabila RM Therapeutics. Pharmacology Purpose: To understand the effect and mechanism of bevacizumab in inbiting wound healing on primary human Tenon's capsule fibroblasts (HTF) in vitro. Methods: HTF was cultured in RPMI media and bevacizumab was added to study the effect of bevacizumab on HTF in vitro at a concentration of 0.25,1.25,6.25 and 12.5 mg/mL. The HTF morphology was identified using vimentin antibody and DAPI staining under immunofluorescent images. MTT assay was done to assess fibroblast cells viability and cell death. The results were compared with mitomycin C. 2013 Thesis https://ir.uitm.edu.my/id/eprint/72214/ https://ir.uitm.edu.my/id/eprint/72214/1/72214.pdf text en public degree Universiti Teknologi MARA (UiTM) Faculty of Medicine Vasudevan, Sushil Kumar
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Vasudevan, Sushil Kumar
topic	RM Therapeutics Pharmacology
spellingShingle	RM Therapeutics Pharmacology Baharudin, Nurul Nabila The effects of bevacizumab on human Tenon’s fibroblasts: an in vitro study / Nurul Nabila Baharudin
description	Purpose: To understand the effect and mechanism of bevacizumab in inbiting wound healing on primary human Tenon's capsule fibroblasts (HTF) in vitro. Methods: HTF was cultured in RPMI media and bevacizumab was added to study the effect of bevacizumab on HTF in vitro at a concentration of 0.25,1.25,6.25 and 12.5 mg/mL. The HTF morphology was identified using vimentin antibody and DAPI staining under immunofluorescent images. MTT assay was done to assess fibroblast cells viability and cell death. The results were compared with mitomycin C.
format	Thesis
qualification_level	Bachelor degree
author	Baharudin, Nurul Nabila
author_facet	Baharudin, Nurul Nabila
author_sort	Baharudin, Nurul Nabila
title	The effects of bevacizumab on human Tenon’s fibroblasts: an in vitro study / Nurul Nabila Baharudin
title_short	The effects of bevacizumab on human Tenon’s fibroblasts: an in vitro study / Nurul Nabila Baharudin
title_full	The effects of bevacizumab on human Tenon’s fibroblasts: an in vitro study / Nurul Nabila Baharudin
title_fullStr	The effects of bevacizumab on human Tenon’s fibroblasts: an in vitro study / Nurul Nabila Baharudin
title_full_unstemmed	The effects of bevacizumab on human Tenon’s fibroblasts: an in vitro study / Nurul Nabila Baharudin
title_sort	effects of bevacizumab on human tenon’s fibroblasts: an in vitro study / nurul nabila baharudin
granting_institution	Universiti Teknologi MARA (UiTM)
granting_department	Faculty of Medicine
publishDate	2013
url	https://ir.uitm.edu.my/id/eprint/72214/1/72214.pdf
_version_	1794191891893321728

The effects of bevacizumab on human Tenon’s fibroblasts: an in vitro study / Nurul Nabila Baharudin

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