Revisiting renal transplant MTAC questionnaire on immunosuppressive medications knowledge in post kidney transplant recipients: item generation & content validation / Nik Aisyah Najwa Nik Mustaffa Shapri

Objectives: Kidney transplant recipients who have better knowledge of immunosuppressants have higher adherence to immunosuppressants and are associated with better overall treatment outcomes. Questionnaires are commonly used to evaluate kidney transplant recipients’ immunosuppressant knowledge eithe...

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Main Author:	Nik Mustaffa Shapri, Nik Aisyah Najwa
Format:	Thesis
Language:	English
Published:	2022
Subjects:	Transplantation of organs tissues etc.
Online Access:	https://ir.uitm.edu.my/id/eprint/72730/2/72730.pdf
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id	my-uitm-ir.72730
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spelling	my-uitm-ir.727302023-02-01T09:01:33Z Revisiting renal transplant MTAC questionnaire on immunosuppressive medications knowledge in post kidney transplant recipients: item generation & content validation / Nik Aisyah Najwa Nik Mustaffa Shapri 2022 Nik Mustaffa Shapri, Nik Aisyah Najwa Transplantation of organs, tissues, etc. Objectives: Kidney transplant recipients who have better knowledge of immunosuppressants have higher adherence to immunosuppressants and are associated with better overall treatment outcomes. Questionnaires are commonly used to evaluate kidney transplant recipients’ immunosuppressant knowledge either as the primary or surrogate measured endpoints to educational interventions both in practice and clinical research. Several questionnaires are available to evaluate immunosuppressant knowledge, but allshowed insufficient content validity. The questionnaire used in Renal Transplant Medication Therapy Adherence Clinic (RTMTAC) is not yet validated. This study aims to revise the content of the RTMTAC questionnaire (RTMTACq). Method & study design: Firstly, preliminary items were generated based on domains and sub domains that were previously identified. Secondly, the items’ content was validated in a 3-round Delphi study by an expert panel of 11 renal pharmacists. The experts rated the items’ relevance, comprehensibility, and comprehensiveness. Items with ≥ 75% of experts’ agreement were considered relevant. Finally, the relevant items were translated into the dual language of Bahasa Malaysia and English through a forward-backward translation process by 3 external translators and 2 researchers. Results: A total of 24 preliminary items were generated. From 17 experts approached, 12 (71%) agreed to participate and 11 out of the 12 (92%) completed the 3-round Delphi study. In Round 1 Delphi study, 20 out of 24 preliminary items were relevant and 9 new items were suggested. In Round 2, 13 preliminary items were rated of which 8 were relevant. In Round 3, 5 preliminary items were rated and 1 was relevant. The final experts’ revision produced 27 items. Conclusion: This study laid the foundation for a validated questionnaire on immunosuppressive medications in kidney transplant recipients through the identification of a set of relevant and comprehensive items. A content validated RTMTACq consisting of 27 items were produced. Future studies should continue with face validity assessment through cognitive interviews with kidney transplant recipients. Accurate evaluation of immunosuppressant knowledge through a validated questionnaire will help to formulate tailored educational interventions for better treatment outcomes 2022 Thesis https://ir.uitm.edu.my/id/eprint/72730/ https://ir.uitm.edu.my/id/eprint/72730/2/72730.pdf text en public masters Universiti Teknologi MARA (UiTM) Faculty of Pharmacy Ibrahim, Norkasihan
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Ibrahim, Norkasihan
topic	Transplantation of organs tissues etc.
spellingShingle	Transplantation of organs tissues etc. Nik Mustaffa Shapri, Nik Aisyah Najwa Revisiting renal transplant MTAC questionnaire on immunosuppressive medications knowledge in post kidney transplant recipients: item generation & content validation / Nik Aisyah Najwa Nik Mustaffa Shapri
description	Objectives: Kidney transplant recipients who have better knowledge of immunosuppressants have higher adherence to immunosuppressants and are associated with better overall treatment outcomes. Questionnaires are commonly used to evaluate kidney transplant recipients’ immunosuppressant knowledge either as the primary or surrogate measured endpoints to educational interventions both in practice and clinical research. Several questionnaires are available to evaluate immunosuppressant knowledge, but allshowed insufficient content validity. The questionnaire used in Renal Transplant Medication Therapy Adherence Clinic (RTMTAC) is not yet validated. This study aims to revise the content of the RTMTAC questionnaire (RTMTACq). Method & study design: Firstly, preliminary items were generated based on domains and sub domains that were previously identified. Secondly, the items’ content was validated in a 3-round Delphi study by an expert panel of 11 renal pharmacists. The experts rated the items’ relevance, comprehensibility, and comprehensiveness. Items with ≥ 75% of experts’ agreement were considered relevant. Finally, the relevant items were translated into the dual language of Bahasa Malaysia and English through a forward-backward translation process by 3 external translators and 2 researchers. Results: A total of 24 preliminary items were generated. From 17 experts approached, 12 (71%) agreed to participate and 11 out of the 12 (92%) completed the 3-round Delphi study. In Round 1 Delphi study, 20 out of 24 preliminary items were relevant and 9 new items were suggested. In Round 2, 13 preliminary items were rated of which 8 were relevant. In Round 3, 5 preliminary items were rated and 1 was relevant. The final experts’ revision produced 27 items. Conclusion: This study laid the foundation for a validated questionnaire on immunosuppressive medications in kidney transplant recipients through the identification of a set of relevant and comprehensive items. A content validated RTMTACq consisting of 27 items were produced. Future studies should continue with face validity assessment through cognitive interviews with kidney transplant recipients. Accurate evaluation of immunosuppressant knowledge through a validated questionnaire will help to formulate tailored educational interventions for better treatment outcomes
format	Thesis
qualification_level	Master's degree
author	Nik Mustaffa Shapri, Nik Aisyah Najwa
author_facet	Nik Mustaffa Shapri, Nik Aisyah Najwa
author_sort	Nik Mustaffa Shapri, Nik Aisyah Najwa
title	Revisiting renal transplant MTAC questionnaire on immunosuppressive medications knowledge in post kidney transplant recipients: item generation & content validation / Nik Aisyah Najwa Nik Mustaffa Shapri
title_short	Revisiting renal transplant MTAC questionnaire on immunosuppressive medications knowledge in post kidney transplant recipients: item generation & content validation / Nik Aisyah Najwa Nik Mustaffa Shapri
title_full	Revisiting renal transplant MTAC questionnaire on immunosuppressive medications knowledge in post kidney transplant recipients: item generation & content validation / Nik Aisyah Najwa Nik Mustaffa Shapri
title_fullStr	Revisiting renal transplant MTAC questionnaire on immunosuppressive medications knowledge in post kidney transplant recipients: item generation & content validation / Nik Aisyah Najwa Nik Mustaffa Shapri
title_full_unstemmed	Revisiting renal transplant MTAC questionnaire on immunosuppressive medications knowledge in post kidney transplant recipients: item generation & content validation / Nik Aisyah Najwa Nik Mustaffa Shapri
title_sort	revisiting renal transplant mtac questionnaire on immunosuppressive medications knowledge in post kidney transplant recipients: item generation & content validation / nik aisyah najwa nik mustaffa shapri
granting_institution	Universiti Teknologi MARA (UiTM)
granting_department	Faculty of Pharmacy
publishDate	2022
url	https://ir.uitm.edu.my/id/eprint/72730/2/72730.pdf
_version_	1783735959207018496

Revisiting renal transplant MTAC questionnaire on immunosuppressive medications knowledge in post kidney transplant recipients: item generation & content validation / Nik Aisyah Najwa Nik Mustaffa Shapri

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