WRL68-CYP3A4 and WRL68-CYP2C9 mutagenesis in vitro drug metabolism models for the assessment drug-herb interactions / Nurliana Abd Mutalib
In vitro screening of drug interactions is one of the most important steps in early drug discovery. Inhibition and stimulation of the phase 1 metabolism enzymes known as CYP450 isozymes is the most prominent form of drug interactions. More reliable and high specificity in vitro models are needed to...
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| Format: | Thesis |
| Language: | English |
| Published: |
2022
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| Subjects: | |
| Online Access: | https://ir.uitm.edu.my/id/eprint/75653/1/75653.pdf |
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