In vitro evaluation of small molecules inhibitory activity against APOBEC3B cytosine deaminase enzyme / Maryan Mohamud Mohamed
Human APOBEC3B (A3B) is a member of the APOBEC3 (A3) family of cytidine deaminases, which function as DNA mutators and restrict viral pathogens and endogenous retrotransposons. APOBEC3B has both C-terminal catalytic (CTD) and N-terminal pseudo-catalytic (NTD) of zinc domains, only the CTD in APOBEC3...
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| Format: | Thesis |
| Language: | English |
| Published: |
2022
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| Online Access: | https://ir.uitm.edu.my/id/eprint/78077/1/78077.pdf |
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