Studies of chitosan thionine-reduced graphene oxide nanocomposite as electrode for ganoderma disease biosensor / Muhammad Aidil Ibrahim

Biosensor is a device that applies biological components to detect target substances involving electrochemistry. In this research, DNA-based biosensor was developed to sensitively detect Ganoderma boninense (GB) which is a fungus that causes basal stem rot to oil palm trees. The DNA-based biosensor...

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Main Author: Ibrahim, Muhammad Aidil
Format: Thesis
Language:English
Published: 2019
Subjects:
Online Access:https://ir.uitm.edu.my/id/eprint/83023/1/83023.pdf
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spelling my-uitm-ir.830232024-02-07T00:17:36Z Studies of chitosan thionine-reduced graphene oxide nanocomposite as electrode for ganoderma disease biosensor / Muhammad Aidil Ibrahim 2019 Ibrahim, Muhammad Aidil Electrolytes, electrolyte solutions Biosensor is a device that applies biological components to detect target substances involving electrochemistry. In this research, DNA-based biosensor was developed to sensitively detect Ganoderma boninense (GB) which is a fungus that causes basal stem rot to oil palm trees. The DNA-based biosensor applies indium-tin-oxide (ITO) coated glass electrode fabricated with materials that enhances the electrochemical properties and the sensitivity of the sensor. The electroconductive reduced graphene oxide (rGO) was used to fabricate ITO electrode as it promotes electroconductivity which allows the sensor to be more sensitive. Another material used, thionine, has a large amount of amino groups to promote immobilization of DNA strands onto the electrode. The composition of thionine with 0.1 mg/mL rGO was successfully determined to induce highest stability to rGO molecules when operating with water-based solvents as thionine makes it more hydrophilic. 2019 Thesis https://ir.uitm.edu.my/id/eprint/83023/ https://ir.uitm.edu.my/id/eprint/83023/1/83023.pdf text en public phd doctoral Universiti Teknologi MARA (UiTM) Faculty of Applied Sciences Hassan, Oskar Hasdinor
institution Universiti Teknologi MARA
collection UiTM Institutional Repository
language English
advisor Hassan, Oskar Hasdinor
topic Electrolytes
electrolyte solutions
spellingShingle Electrolytes
electrolyte solutions
Ibrahim, Muhammad Aidil
Studies of chitosan thionine-reduced graphene oxide nanocomposite as electrode for ganoderma disease biosensor / Muhammad Aidil Ibrahim
description Biosensor is a device that applies biological components to detect target substances involving electrochemistry. In this research, DNA-based biosensor was developed to sensitively detect Ganoderma boninense (GB) which is a fungus that causes basal stem rot to oil palm trees. The DNA-based biosensor applies indium-tin-oxide (ITO) coated glass electrode fabricated with materials that enhances the electrochemical properties and the sensitivity of the sensor. The electroconductive reduced graphene oxide (rGO) was used to fabricate ITO electrode as it promotes electroconductivity which allows the sensor to be more sensitive. Another material used, thionine, has a large amount of amino groups to promote immobilization of DNA strands onto the electrode. The composition of thionine with 0.1 mg/mL rGO was successfully determined to induce highest stability to rGO molecules when operating with water-based solvents as thionine makes it more hydrophilic.
format Thesis
qualification_name Doctor of Philosophy (PhD.)
qualification_level Doctorate
author Ibrahim, Muhammad Aidil
author_facet Ibrahim, Muhammad Aidil
author_sort Ibrahim, Muhammad Aidil
title Studies of chitosan thionine-reduced graphene oxide nanocomposite as electrode for ganoderma disease biosensor / Muhammad Aidil Ibrahim
title_short Studies of chitosan thionine-reduced graphene oxide nanocomposite as electrode for ganoderma disease biosensor / Muhammad Aidil Ibrahim
title_full Studies of chitosan thionine-reduced graphene oxide nanocomposite as electrode for ganoderma disease biosensor / Muhammad Aidil Ibrahim
title_fullStr Studies of chitosan thionine-reduced graphene oxide nanocomposite as electrode for ganoderma disease biosensor / Muhammad Aidil Ibrahim
title_full_unstemmed Studies of chitosan thionine-reduced graphene oxide nanocomposite as electrode for ganoderma disease biosensor / Muhammad Aidil Ibrahim
title_sort studies of chitosan thionine-reduced graphene oxide nanocomposite as electrode for ganoderma disease biosensor / muhammad aidil ibrahim
granting_institution Universiti Teknologi MARA (UiTM)
granting_department Faculty of Applied Sciences
publishDate 2019
url https://ir.uitm.edu.my/id/eprint/83023/1/83023.pdf
_version_ 1794191961105629184