Safety assessment and bioavailability study of Brucea javanica seeds aqueous extract / Farahdina Man

Safety assessment and bioavailability study of Brucea javanica seeds aqueous extract / Farahdina Man

Diabetes mellitus is a disease that is increasing worldwide. The aqueous decoction of Brucea javanica (Simaroubaceae) seeds are traditionally used as anti-diabetic medicine. Standardization of an extract ensures the therapeutic effect is reproducible. The aim of the research is to evaluate the safet...

Full description

Saved in:
Bibliographic Details
Main Author: Man, Farahdina
Format: Thesis
Language:English
Published: 2018
Subjects:
Medical education
Medical schools
Research
RZ Other systems of medicine
Online Access:https://ir.uitm.edu.my/id/eprint/84259/1/84259.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!
id my-uitm-ir.84259
record_format uketd_dc
spelling my-uitm-ir.842592024-02-27T00:40:24Z Safety assessment and bioavailability study of Brucea javanica seeds aqueous extract / Farahdina Man 2018 Man, Farahdina Medical education. Medical schools. Research RZ Other systems of medicine Diabetes mellitus is a disease that is increasing worldwide. The aqueous decoction of Brucea javanica (Simaroubaceae) seeds are traditionally used as anti-diabetic medicine. Standardization of an extract ensures the therapeutic effect is reproducible. The aim of the research is to evaluate the safety of daily consumption of a standardized aqueous extract and to develop of a sensitive Liquid Chromatographytandem Mass Spectrometry (LC-MS/MS) system to establish the bioavailability and pharmacokinetics study of bruceine D and E. A High Performance Liquid Chromatography-Photodiode Array (HPLC-PDA) method was developed and validated for the determination of both bruceines in the aqueous extract. 2018 Thesis https://ir.uitm.edu.my/id/eprint/84259/ https://ir.uitm.edu.my/id/eprint/84259/1/84259.pdf text en public masters Universiti Teknologi MARA (UiTM) Faculty of Pharmacy Choo, Chee Yan
institution Universiti Teknologi MARA
collection UiTM Institutional Repository
language English
advisor Choo, Chee Yan
topic Medical education
Medical schools
Research
RZ Other systems of medicine
spellingShingle Medical education
Medical schools
Research
RZ Other systems of medicine
Man, Farahdina
Safety assessment and bioavailability study of Brucea javanica seeds aqueous extract / Farahdina Man
description Diabetes mellitus is a disease that is increasing worldwide. The aqueous decoction of Brucea javanica (Simaroubaceae) seeds are traditionally used as anti-diabetic medicine. Standardization of an extract ensures the therapeutic effect is reproducible. The aim of the research is to evaluate the safety of daily consumption of a standardized aqueous extract and to develop of a sensitive Liquid Chromatographytandem Mass Spectrometry (LC-MS/MS) system to establish the bioavailability and pharmacokinetics study of bruceine D and E. A High Performance Liquid Chromatography-Photodiode Array (HPLC-PDA) method was developed and validated for the determination of both bruceines in the aqueous extract.
format Thesis
qualification_level Master's degree
author Man, Farahdina
author_facet Man, Farahdina
author_sort Man, Farahdina
title Safety assessment and bioavailability study of Brucea javanica seeds aqueous extract / Farahdina Man
title_short Safety assessment and bioavailability study of Brucea javanica seeds aqueous extract / Farahdina Man
title_full Safety assessment and bioavailability study of Brucea javanica seeds aqueous extract / Farahdina Man
title_fullStr Safety assessment and bioavailability study of Brucea javanica seeds aqueous extract / Farahdina Man
title_full_unstemmed Safety assessment and bioavailability study of Brucea javanica seeds aqueous extract / Farahdina Man
title_sort safety assessment and bioavailability study of brucea javanica seeds aqueous extract / farahdina man
granting_institution Universiti Teknologi MARA (UiTM)
granting_department Faculty of Pharmacy
publishDate 2018
url https://ir.uitm.edu.my/id/eprint/84259/1/84259.pdf
_version_ 1794191986955124736

Similar Items