Unravelling the mechanisms underlying the immunometablic changes in gestational diabetes mellitus animal model that is induced through biochemical, pharmacological and lifestyle factors / Siti Hajar Abdul Aziz

Gestational diabetes mellitus (GDM) is defined as diabetes that is not clearly apparent diabetes, diagnosed in the second or third trimester of pregnancy. Women diagnosed with diabetes during gestation have an increased incidence of complications during and after pregnancy. Thus, this study attempts...

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Main Author:	Abdul Aziz, Siti Hajar
Format:	Thesis
Language:	English
Published:	2018
Online Access:	https://ir.uitm.edu.my/id/eprint/86111/1/86111.pdf
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id	my-uitm-ir.86111
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spelling	my-uitm-ir.861112024-03-27T02:41:09Z Unravelling the mechanisms underlying the immunometablic changes in gestational diabetes mellitus animal model that is induced through biochemical, pharmacological and lifestyle factors / Siti Hajar Abdul Aziz 2018 Abdul Aziz, Siti Hajar Gestational diabetes mellitus (GDM) is defined as diabetes that is not clearly apparent diabetes, diagnosed in the second or third trimester of pregnancy. Women diagnosed with diabetes during gestation have an increased incidence of complications during and after pregnancy. Thus, this study attempts to develop a GDM animal model in female Sprague-Dawley rats. This study comprises of two phases; first phase showed comparison between four groups with different diets with GDM fed with high fat sucrose diet group was chosen in GDM animal model in Phase 2 of this study, as the group show the relative elevated level of glucose and lipid profiles. Rats were fed with high fat sucrose diet, impregnated, and induced with Streptozotocin and Nicotinamide on (D0). 2018 Thesis https://ir.uitm.edu.my/id/eprint/86111/ https://ir.uitm.edu.my/id/eprint/86111/1/86111.pdf text en public masters Universiti Teknologi MARA (UiTM) Faculty of Pharmacy Adam, Aishah
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Adam, Aishah
description	Gestational diabetes mellitus (GDM) is defined as diabetes that is not clearly apparent diabetes, diagnosed in the second or third trimester of pregnancy. Women diagnosed with diabetes during gestation have an increased incidence of complications during and after pregnancy. Thus, this study attempts to develop a GDM animal model in female Sprague-Dawley rats. This study comprises of two phases; first phase showed comparison between four groups with different diets with GDM fed with high fat sucrose diet group was chosen in GDM animal model in Phase 2 of this study, as the group show the relative elevated level of glucose and lipid profiles. Rats were fed with high fat sucrose diet, impregnated, and induced with Streptozotocin and Nicotinamide on (D0).
format	Thesis
qualification_level	Master's degree
author	Abdul Aziz, Siti Hajar
spellingShingle	Abdul Aziz, Siti Hajar Unravelling the mechanisms underlying the immunometablic changes in gestational diabetes mellitus animal model that is induced through biochemical, pharmacological and lifestyle factors / Siti Hajar Abdul Aziz
author_facet	Abdul Aziz, Siti Hajar
author_sort	Abdul Aziz, Siti Hajar
title	Unravelling the mechanisms underlying the immunometablic changes in gestational diabetes mellitus animal model that is induced through biochemical, pharmacological and lifestyle factors / Siti Hajar Abdul Aziz
title_short	Unravelling the mechanisms underlying the immunometablic changes in gestational diabetes mellitus animal model that is induced through biochemical, pharmacological and lifestyle factors / Siti Hajar Abdul Aziz
title_full	Unravelling the mechanisms underlying the immunometablic changes in gestational diabetes mellitus animal model that is induced through biochemical, pharmacological and lifestyle factors / Siti Hajar Abdul Aziz
title_fullStr	Unravelling the mechanisms underlying the immunometablic changes in gestational diabetes mellitus animal model that is induced through biochemical, pharmacological and lifestyle factors / Siti Hajar Abdul Aziz
title_full_unstemmed	Unravelling the mechanisms underlying the immunometablic changes in gestational diabetes mellitus animal model that is induced through biochemical, pharmacological and lifestyle factors / Siti Hajar Abdul Aziz
title_sort	unravelling the mechanisms underlying the immunometablic changes in gestational diabetes mellitus animal model that is induced through biochemical, pharmacological and lifestyle factors / siti hajar abdul aziz
granting_institution	Universiti Teknologi MARA (UiTM)
granting_department	Faculty of Pharmacy
publishDate	2018
url	https://ir.uitm.edu.my/id/eprint/86111/1/86111.pdf
_version_	1804889751024566272

Unravelling the mechanisms underlying the immunometablic changes in gestational diabetes mellitus animal model that is induced through biochemical, pharmacological and lifestyle factors / Siti Hajar Abdul Aziz

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