Depressive symptoms among patients with systemic lupus erythematosus in rheumatology clinic: associated factors and willingness to seek psychiatric help / Nur Adlina Tajul Arifin

Introduction: Long-standing chronic illnesses such as Systemic lupus erythematosus (SLE) patients are at high risk for depression due to non-resolving diseases that might affect the quality of patients' lives. This study aimed to establish the factors associated with depressive symptoms among p...

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Main Author: Tajul Arifin, Dr. Nur Adlina
Format: Thesis
Language:English
Published: 2021
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Online Access:https://ir.uitm.edu.my/id/eprint/93976/2/93976.pdf
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spelling my-uitm-ir.939762024-08-22T03:44:28Z Depressive symptoms among patients with systemic lupus erythematosus in rheumatology clinic: associated factors and willingness to seek psychiatric help / Nur Adlina Tajul Arifin 2021 Tajul Arifin, Dr. Nur Adlina Depression. Affective disorders Introduction: Long-standing chronic illnesses such as Systemic lupus erythematosus (SLE) patients are at high risk for depression due to non-resolving diseases that might affect the quality of patients' lives. This study aimed to establish the factors associated with depressive symptoms among patients with SLE and willingness to seek psychiatric help in the rheumatology clinic. Method: A single-centre cross-sectional study among SLE patients. Patients were given WHO Quality of Life-BREF (WHOQOL-BREF) questionnaires and The Center for Epidemiological Studies–Depression Scale (CESD) to assess for quality of life (QoL) and depressive symptoms. Cumulative organ damage (Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index), total steroids in 3 months were recorded. Disease activity was measured using the British Isles Lupus Assessment Group's (BILAG 2004). The presence of fibromyalgia is also screened. CESD score ≥ 16 shows significant depressive symptoms. Univariate analysis is used to study the factors associated with depressive disorders and the impact of depressive symptoms in compliance and quality of life. All patients who had significant depressive symptoms were then referred to psychiatry. Result: 165 patients with SLE participated in this study. Based on the CESD score, 57 (34.54%) patients scored ≥16, which indicated depressive symptoms, and 108 (65.45%) patients scored <16, which indicated no depressive symptoms. We discovered no significant association of depressive symptoms with sociodemographic data, prednisolone dosage, SDI and disease activities. However, the patient who had fibromyalgia in SLE showed substantial depressive symptoms with a p-value of 0.049. The study showed that patients with depression had a low quality of life (QoL) and missed medication. Out of 57 patients with depressive symptoms, 15 (26.3%) agreed for psychiatric evaluation, while 32 (56.14%) refused psychiatric evaluation. Conclusion: one-third of our SLE patients had depressive symptoms associated with lower quality of life and poor compliance to treatment. A holistic approach to patient management would include identifying these patients to improve patients' outcomes. However, we did not find any factors associated with depressive symptoms to identify patients subjected to screening for depression. Another critical finding is patients' unwillingness to seek psychiatric help. Faculty of Medicine 2021 Thesis https://ir.uitm.edu.my/id/eprint/93976/ https://ir.uitm.edu.my/id/eprint/93976/2/93976.pdf text en public masters Universiti Teknologi MARA Faculty of Medicine
institution Universiti Teknologi MARA
collection UiTM Institutional Repository
language English
topic Depression
Affective disorders
spellingShingle Depression
Affective disorders
Tajul Arifin, Dr. Nur Adlina
Depressive symptoms among patients with systemic lupus erythematosus in rheumatology clinic: associated factors and willingness to seek psychiatric help / Nur Adlina Tajul Arifin
description Introduction: Long-standing chronic illnesses such as Systemic lupus erythematosus (SLE) patients are at high risk for depression due to non-resolving diseases that might affect the quality of patients' lives. This study aimed to establish the factors associated with depressive symptoms among patients with SLE and willingness to seek psychiatric help in the rheumatology clinic. Method: A single-centre cross-sectional study among SLE patients. Patients were given WHO Quality of Life-BREF (WHOQOL-BREF) questionnaires and The Center for Epidemiological Studies–Depression Scale (CESD) to assess for quality of life (QoL) and depressive symptoms. Cumulative organ damage (Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index), total steroids in 3 months were recorded. Disease activity was measured using the British Isles Lupus Assessment Group's (BILAG 2004). The presence of fibromyalgia is also screened. CESD score ≥ 16 shows significant depressive symptoms. Univariate analysis is used to study the factors associated with depressive disorders and the impact of depressive symptoms in compliance and quality of life. All patients who had significant depressive symptoms were then referred to psychiatry. Result: 165 patients with SLE participated in this study. Based on the CESD score, 57 (34.54%) patients scored ≥16, which indicated depressive symptoms, and 108 (65.45%) patients scored <16, which indicated no depressive symptoms. We discovered no significant association of depressive symptoms with sociodemographic data, prednisolone dosage, SDI and disease activities. However, the patient who had fibromyalgia in SLE showed substantial depressive symptoms with a p-value of 0.049. The study showed that patients with depression had a low quality of life (QoL) and missed medication. Out of 57 patients with depressive symptoms, 15 (26.3%) agreed for psychiatric evaluation, while 32 (56.14%) refused psychiatric evaluation. Conclusion: one-third of our SLE patients had depressive symptoms associated with lower quality of life and poor compliance to treatment. A holistic approach to patient management would include identifying these patients to improve patients' outcomes. However, we did not find any factors associated with depressive symptoms to identify patients subjected to screening for depression. Another critical finding is patients' unwillingness to seek psychiatric help.
format Thesis
qualification_level Master's degree
author Tajul Arifin, Dr. Nur Adlina
author_facet Tajul Arifin, Dr. Nur Adlina
author_sort Tajul Arifin, Dr. Nur Adlina
title Depressive symptoms among patients with systemic lupus erythematosus in rheumatology clinic: associated factors and willingness to seek psychiatric help / Nur Adlina Tajul Arifin
title_short Depressive symptoms among patients with systemic lupus erythematosus in rheumatology clinic: associated factors and willingness to seek psychiatric help / Nur Adlina Tajul Arifin
title_full Depressive symptoms among patients with systemic lupus erythematosus in rheumatology clinic: associated factors and willingness to seek psychiatric help / Nur Adlina Tajul Arifin
title_fullStr Depressive symptoms among patients with systemic lupus erythematosus in rheumatology clinic: associated factors and willingness to seek psychiatric help / Nur Adlina Tajul Arifin
title_full_unstemmed Depressive symptoms among patients with systemic lupus erythematosus in rheumatology clinic: associated factors and willingness to seek psychiatric help / Nur Adlina Tajul Arifin
title_sort depressive symptoms among patients with systemic lupus erythematosus in rheumatology clinic: associated factors and willingness to seek psychiatric help / nur adlina tajul arifin
granting_institution Universiti Teknologi MARA
granting_department Faculty of Medicine
publishDate 2021
url https://ir.uitm.edu.my/id/eprint/93976/2/93976.pdf
_version_ 1811768779155177472