Prevalence of postpartum-abnormal glucose tolerance (P-AGT) and its associated factors among women with gestational diabetes mellitus (GDM) in Klang, Selangor / Shafawati Akmal Adam

Introduction: Women with gestational diabetes mellitus (GDM) have a risk to develop diabetes at least seven times higher than other women. The study aimed to determine the prevalence of postpartum-abnormal glucose tolerance (P-AGT), the level of knowledge on GDM and the associated factors for P-AGT...

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Main Author:	Adam, Shafawati Akmal
Format:	Thesis
Language:	English
Published:	2023
Subjects:	Diabetes Mellitus
Online Access:	https://ir.uitm.edu.my/id/eprint/94038/1/94038.pdf
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id	my-uitm-ir.94038
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spelling	my-uitm-ir.940382024-04-29T02:27:48Z Prevalence of postpartum-abnormal glucose tolerance (P-AGT) and its associated factors among women with gestational diabetes mellitus (GDM) in Klang, Selangor / Shafawati Akmal Adam 2023 Adam, Shafawati Akmal Diabetes Mellitus Introduction: Women with gestational diabetes mellitus (GDM) have a risk to develop diabetes at least seven times higher than other women. The study aimed to determine the prevalence of postpartum-abnormal glucose tolerance (P-AGT), the level of knowledge on GDM and the associated factors for P-AGT among postpartum women with GDM attending public health clinics in Klang. Methods: This cross-sectional study used convenience sampling and was conducted among GDM women attending the oral glucose tolerance test (OGTT) at six to 12 weeks postpartum. Sociodemographic factors, clinical characteristics, knowledge about GDM (using a validated questionnaire, GDMKQ) and postpartum OGTT results were collected. Results: The study included 439 participants. The majority were below the age of 35 years old (71.8%), of Malay ethnicity (82.7%), and demonstrated adequate knowledge of GDM (92.9%). The prevalence of P-AGT was found to be 28.9% (95% CI:24.7, 33.4). Multiple logistic regression analysis showed gestational age upon GDM diagnosis <24 weeks (aOR: 1.85, 95% CI: 1.17, 2.92; p = 0.009), abnormal 2-hour postprandial (2HPP) level (>7.8mmol/L) upon GDM diagnosis (aOR: 2.95, 95% CI: 1.74, 5.00; p < 0.001) and first-degree family history of diabetes (aOR: 1.55, 95% CI: 1.01, 2.39; p = 0.047) were significantly associated with P-AGT. Conclusion: This study revealed higher prevalence of P-AGT compared to previous local studies. Targeted monitoring and management strategies are crucial, especially for women diagnosed with GDM before 24 weeks of gestation, those who had abnormal 2HPP level upon GDM diagnosis and those with first-degree family history of DM to prevent the occurrence of P-AGT. 2023 Thesis https://ir.uitm.edu.my/id/eprint/94038/ https://ir.uitm.edu.my/id/eprint/94038/1/94038.pdf text en public masters Universiti Teknologi MARA (Kampus Sg. Buloh) Faculty of Medicine Md Yasin, Dr. Mazapuspavina
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Md Yasin, Dr. Mazapuspavina
topic	Diabetes Mellitus
spellingShingle	Diabetes Mellitus Adam, Shafawati Akmal Prevalence of postpartum-abnormal glucose tolerance (P-AGT) and its associated factors among women with gestational diabetes mellitus (GDM) in Klang, Selangor / Shafawati Akmal Adam
description	Introduction: Women with gestational diabetes mellitus (GDM) have a risk to develop diabetes at least seven times higher than other women. The study aimed to determine the prevalence of postpartum-abnormal glucose tolerance (P-AGT), the level of knowledge on GDM and the associated factors for P-AGT among postpartum women with GDM attending public health clinics in Klang. Methods: This cross-sectional study used convenience sampling and was conducted among GDM women attending the oral glucose tolerance test (OGTT) at six to 12 weeks postpartum. Sociodemographic factors, clinical characteristics, knowledge about GDM (using a validated questionnaire, GDMKQ) and postpartum OGTT results were collected. Results: The study included 439 participants. The majority were below the age of 35 years old (71.8%), of Malay ethnicity (82.7%), and demonstrated adequate knowledge of GDM (92.9%). The prevalence of P-AGT was found to be 28.9% (95% CI:24.7, 33.4). Multiple logistic regression analysis showed gestational age upon GDM diagnosis <24 weeks (aOR: 1.85, 95% CI: 1.17, 2.92; p = 0.009), abnormal 2-hour postprandial (2HPP) level (>7.8mmol/L) upon GDM diagnosis (aOR: 2.95, 95% CI: 1.74, 5.00; p < 0.001) and first-degree family history of diabetes (aOR: 1.55, 95% CI: 1.01, 2.39; p = 0.047) were significantly associated with P-AGT. Conclusion: This study revealed higher prevalence of P-AGT compared to previous local studies. Targeted monitoring and management strategies are crucial, especially for women diagnosed with GDM before 24 weeks of gestation, those who had abnormal 2HPP level upon GDM diagnosis and those with first-degree family history of DM to prevent the occurrence of P-AGT.
format	Thesis
qualification_level	Master's degree
author	Adam, Shafawati Akmal
author_facet	Adam, Shafawati Akmal
author_sort	Adam, Shafawati Akmal
title	Prevalence of postpartum-abnormal glucose tolerance (P-AGT) and its associated factors among women with gestational diabetes mellitus (GDM) in Klang, Selangor / Shafawati Akmal Adam
title_short	Prevalence of postpartum-abnormal glucose tolerance (P-AGT) and its associated factors among women with gestational diabetes mellitus (GDM) in Klang, Selangor / Shafawati Akmal Adam
title_full	Prevalence of postpartum-abnormal glucose tolerance (P-AGT) and its associated factors among women with gestational diabetes mellitus (GDM) in Klang, Selangor / Shafawati Akmal Adam
title_fullStr	Prevalence of postpartum-abnormal glucose tolerance (P-AGT) and its associated factors among women with gestational diabetes mellitus (GDM) in Klang, Selangor / Shafawati Akmal Adam
title_full_unstemmed	Prevalence of postpartum-abnormal glucose tolerance (P-AGT) and its associated factors among women with gestational diabetes mellitus (GDM) in Klang, Selangor / Shafawati Akmal Adam
title_sort	prevalence of postpartum-abnormal glucose tolerance (p-agt) and its associated factors among women with gestational diabetes mellitus (gdm) in klang, selangor / shafawati akmal adam
granting_institution	Universiti Teknologi MARA (Kampus Sg. Buloh)
granting_department	Faculty of Medicine
publishDate	2023
url	https://ir.uitm.edu.my/id/eprint/94038/1/94038.pdf
_version_	1804889915961376768

Prevalence of postpartum-abnormal glucose tolerance (P-AGT) and its associated factors among women with gestational diabetes mellitus (GDM) in Klang, Selangor / Shafawati Akmal Adam

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