An analytical method for the analysis of prednisolone in tablet formulation by high performance liquid chromatography / Hasnah Abdull
A high performance liquid chromatographic assay with ultraviolet (UV) absorbance at 254 nm was developed for the analysis of prednisolone in samples given. The developed technique was reproducible, selective, reliable and sensitive for the analysis of prednisolone. Samples and an external standard (...
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| Language: | English |
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2005
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| Online Access: | https://ir.uitm.edu.my/id/eprint/98543/1/98543.PDF |
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my-uitm-ir.985432024-07-22T08:44:16Z An analytical method for the analysis of prednisolone in tablet formulation by high performance liquid chromatography / Hasnah Abdull 2005 Abdull, Hasnah RM Therapeutics. Pharmacology RS Pharmacy and materia medica A high performance liquid chromatographic assay with ultraviolet (UV) absorbance at 254 nm was developed for the analysis of prednisolone in samples given. The developed technique was reproducible, selective, reliable and sensitive for the analysis of prednisolone. Samples and an external standard (prednisolone) given were eluted onto a column packed with reverse phase ODS silica gel by a mobile phase composed of distilled water-methanol (60:40, v/v). External standard as calibrators were prepared in concentrations ranging from 50 pg/ml to 250 pg/ml. The calibration curve obtained was linear with correlation factor of 0.99973. Samples were injected at a flow rate of 1.2 ml/min. The developed method was rapid and specific for the quantification of prednisolone drug at a run time of below 5 minutes. 2005 Thesis https://ir.uitm.edu.my/id/eprint/98543/ https://ir.uitm.edu.my/id/eprint/98543/1/98543.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Mohd. Shah, Ismail |
| institution |
Universiti Teknologi MARA |
| collection |
UiTM Institutional Repository |
| language |
English |
| advisor |
Mohd. Shah, Ismail |
| topic |
RM Therapeutics Pharmacology RS Pharmacy and materia medica |
| spellingShingle |
RM Therapeutics Pharmacology RS Pharmacy and materia medica Abdull, Hasnah An analytical method for the analysis of prednisolone in tablet formulation by high performance liquid chromatography / Hasnah Abdull |
| description |
A high performance liquid chromatographic assay with ultraviolet (UV) absorbance at 254 nm was developed for the analysis of prednisolone in samples given. The developed technique was reproducible, selective, reliable and sensitive for the analysis of prednisolone. Samples and an external standard (prednisolone) given were eluted onto a column packed with reverse phase ODS silica gel by a mobile phase composed of distilled water-methanol (60:40, v/v). External standard as calibrators were prepared in concentrations ranging from 50 pg/ml to 250 pg/ml. The calibration curve obtained was linear with correlation factor of 0.99973. Samples were injected at a flow rate of 1.2 ml/min. The developed method was rapid and specific for the quantification of prednisolone drug at a run time of below 5 minutes. |
| format |
Thesis |
| qualification_level |
Bachelor degree |
| author |
Abdull, Hasnah |
| author_facet |
Abdull, Hasnah |
| author_sort |
Abdull, Hasnah |
| title |
An analytical method for the analysis of prednisolone in tablet formulation by high performance liquid chromatography / Hasnah Abdull |
| title_short |
An analytical method for the analysis of prednisolone in tablet formulation by high performance liquid chromatography / Hasnah Abdull |
| title_full |
An analytical method for the analysis of prednisolone in tablet formulation by high performance liquid chromatography / Hasnah Abdull |
| title_fullStr |
An analytical method for the analysis of prednisolone in tablet formulation by high performance liquid chromatography / Hasnah Abdull |
| title_full_unstemmed |
An analytical method for the analysis of prednisolone in tablet formulation by high performance liquid chromatography / Hasnah Abdull |
| title_sort |
analytical method for the analysis of prednisolone in tablet formulation by high performance liquid chromatography / hasnah abdull |
| granting_institution |
Universiti Teknologi MARA (Kampus Puncak Alam) |
| granting_department |
Faculty of Pharmacy |
| publishDate |
2005 |
| url |
https://ir.uitm.edu.my/id/eprint/98543/1/98543.PDF |
| _version_ |
1811768932018683904 |