Design, synthesis and determination of biological activities of stilbene analogue attached to zinc (ii)-cyclen complex / Nafiza Mohd Ismail

The significance of this research is to design, synthesis and determination of biological activities of resveratrol (stilbene) analogue attached to Zn2+-cyclen complex. Three established reactions had been used in order to accomplish the research. First, the 3,5- dimethoxybenzaldehyde was utilizes a...

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Main Author:	Mohd Ismail, Nafiza
Format:	Thesis
Language:	English
Published:	2005
Subjects:	QD Chemistry
Online Access:	https://ir.uitm.edu.my/id/eprint/98655/1/98655.PDF
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id	my-uitm-ir.98655
record_format	uketd_dc
spelling	my-uitm-ir.986552024-07-22T04:32:55Z Design, synthesis and determination of biological activities of stilbene analogue attached to zinc (ii)-cyclen complex / Nafiza Mohd Ismail 2005 Mohd Ismail, Nafiza QD Chemistry RM Therapeutics. Pharmacology The significance of this research is to design, synthesis and determination of biological activities of resveratrol (stilbene) analogue attached to Zn2+-cyclen complex. Three established reactions had been used in order to accomplish the research. First, the 3,5- dimethoxybenzaldehyde was utilizes as a starting material of the Wittig reaction. Subsequently, protection of the 4-iodophenol using TBDMS-C1 to yield 4-iodo-tert- butyldimethylsilylphenylether. Product of the Wittig reaction and 4-iodo-/er/- butyldimethylsilylphenylether were then use to synthesize the stilbene analogue. The synthesized compounds were then, purified by chromatographic techniques and sent for 'H-NMR and UV characterization. The outcomes of this research did not make the grade, and the research was postponed due time constraint. 2005 Thesis https://ir.uitm.edu.my/id/eprint/98655/ https://ir.uitm.edu.my/id/eprint/98655/1/98655.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Mat Jusoh, Mohd Zulkefeli
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Mat Jusoh, Mohd Zulkefeli
topic	QD Chemistry QD Chemistry
spellingShingle	QD Chemistry QD Chemistry Mohd Ismail, Nafiza Design, synthesis and determination of biological activities of stilbene analogue attached to zinc (ii)-cyclen complex / Nafiza Mohd Ismail
description	The significance of this research is to design, synthesis and determination of biological activities of resveratrol (stilbene) analogue attached to Zn2+-cyclen complex. Three established reactions had been used in order to accomplish the research. First, the 3,5- dimethoxybenzaldehyde was utilizes as a starting material of the Wittig reaction. Subsequently, protection of the 4-iodophenol using TBDMS-C1 to yield 4-iodo-tert- butyldimethylsilylphenylether. Product of the Wittig reaction and 4-iodo-/er/- butyldimethylsilylphenylether were then use to synthesize the stilbene analogue. The synthesized compounds were then, purified by chromatographic techniques and sent for 'H-NMR and UV characterization. The outcomes of this research did not make the grade, and the research was postponed due time constraint.
format	Thesis
qualification_level	Bachelor degree
author	Mohd Ismail, Nafiza
author_facet	Mohd Ismail, Nafiza
author_sort	Mohd Ismail, Nafiza
title	Design, synthesis and determination of biological activities of stilbene analogue attached to zinc (ii)-cyclen complex / Nafiza Mohd Ismail
title_short	Design, synthesis and determination of biological activities of stilbene analogue attached to zinc (ii)-cyclen complex / Nafiza Mohd Ismail
title_full	Design, synthesis and determination of biological activities of stilbene analogue attached to zinc (ii)-cyclen complex / Nafiza Mohd Ismail
title_fullStr	Design, synthesis and determination of biological activities of stilbene analogue attached to zinc (ii)-cyclen complex / Nafiza Mohd Ismail
title_full_unstemmed	Design, synthesis and determination of biological activities of stilbene analogue attached to zinc (ii)-cyclen complex / Nafiza Mohd Ismail
title_sort	design, synthesis and determination of biological activities of stilbene analogue attached to zinc (ii)-cyclen complex / nafiza mohd ismail
granting_institution	Universiti Teknologi MARA (Kampus Puncak Alam)
granting_department	Faculty of Pharmacy
publishDate	2005
url	https://ir.uitm.edu.my/id/eprint/98655/1/98655.PDF
_version_	1811768951424679936

Design, synthesis and determination of biological activities of stilbene analogue attached to zinc (ii)-cyclen complex / Nafiza Mohd Ismail

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