Effects of indigenous plant octomeles sumatrana on blood parameters in rats / Khamisah Itim

Octomeles sumatrana also known as 'Binuang" is one of the traditional medicines applied by the enormous Kadazandusun communities in Borneo. Primarily, it is used as tonic or to treat stomachache, bone pain and muscle sprain. The aim of this study is to determine the potential effects and t...

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Main Author:	Itim, Khamisah
Format:	Thesis
Language:	English
Published:	2006
Subjects:	RM Therapeutics Pharmacology RS Pharmacy and materia medica
Online Access:	https://ir.uitm.edu.my/id/eprint/98934/1/98934.PDF
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id	my-uitm-ir.98934
record_format	uketd_dc
spelling	my-uitm-ir.989342024-07-24T08:04:38Z Effects of indigenous plant octomeles sumatrana on blood parameters in rats / Khamisah Itim 2006 Itim, Khamisah RM Therapeutics. Pharmacology RS Pharmacy and materia medica Octomeles sumatrana also known as 'Binuang" is one of the traditional medicines applied by the enormous Kadazandusun communities in Borneo. Primarily, it is used as tonic or to treat stomachache, bone pain and muscle sprain. The aim of this study is to determine the potential effects and toxicity associated with the use of Octomeles sumatrana on blood parameters. Two group of five rats were given either the extracts (treatment group) or normal saline (control group).The water soluble extracts of Octomeles sumatrana bark was administered by gavage with the use of oral needle. Later, the blood samples were obtained by cardiac puncture. No mortality was observed upon administration of OS for both acute and sub acute toxicity study. However, there are changes in the blood parameters when evaluated with the conventional pharmacologic method. The result obtained, revealed the differences between the control and the treatment group biochemical properties. In acute toxicity study, the level of lymphocyte, monocyte and total protein were statistically higher than the control group and there were falls in the level of AST. From sub acute toxicity study, the level of ALT, AST, cholesterol, urea and chloride were statistically lowered in the treatment group compare to the control group. 2006 Thesis https://ir.uitm.edu.my/id/eprint/98934/ https://ir.uitm.edu.my/id/eprint/98934/1/98934.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Sulong, Adnan
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Sulong, Adnan
topic	RM Therapeutics Pharmacology RS Pharmacy and materia medica
spellingShingle	RM Therapeutics Pharmacology RS Pharmacy and materia medica Itim, Khamisah Effects of indigenous plant octomeles sumatrana on blood parameters in rats / Khamisah Itim
description	Octomeles sumatrana also known as 'Binuang" is one of the traditional medicines applied by the enormous Kadazandusun communities in Borneo. Primarily, it is used as tonic or to treat stomachache, bone pain and muscle sprain. The aim of this study is to determine the potential effects and toxicity associated with the use of Octomeles sumatrana on blood parameters. Two group of five rats were given either the extracts (treatment group) or normal saline (control group).The water soluble extracts of Octomeles sumatrana bark was administered by gavage with the use of oral needle. Later, the blood samples were obtained by cardiac puncture. No mortality was observed upon administration of OS for both acute and sub acute toxicity study. However, there are changes in the blood parameters when evaluated with the conventional pharmacologic method. The result obtained, revealed the differences between the control and the treatment group biochemical properties. In acute toxicity study, the level of lymphocyte, monocyte and total protein were statistically higher than the control group and there were falls in the level of AST. From sub acute toxicity study, the level of ALT, AST, cholesterol, urea and chloride were statistically lowered in the treatment group compare to the control group.
format	Thesis
qualification_level	Bachelor degree
author	Itim, Khamisah
author_facet	Itim, Khamisah
author_sort	Itim, Khamisah
title	Effects of indigenous plant octomeles sumatrana on blood parameters in rats / Khamisah Itim
title_short	Effects of indigenous plant octomeles sumatrana on blood parameters in rats / Khamisah Itim
title_full	Effects of indigenous plant octomeles sumatrana on blood parameters in rats / Khamisah Itim
title_fullStr	Effects of indigenous plant octomeles sumatrana on blood parameters in rats / Khamisah Itim
title_full_unstemmed	Effects of indigenous plant octomeles sumatrana on blood parameters in rats / Khamisah Itim
title_sort	effects of indigenous plant octomeles sumatrana on blood parameters in rats / khamisah itim
granting_institution	Universiti Teknologi MARA (Kampus Puncak Alam)
granting_department	Faculty of Pharmacy
publishDate	2006
url	https://ir.uitm.edu.my/id/eprint/98934/1/98934.PDF
_version_	1811768969872277504

Effects of indigenous plant octomeles sumatrana on blood parameters in rats / Khamisah Itim

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