Evaluation of Malaysian herbs on artemia salina toxicity assay / Rozita Hanim Abdul Rahim

This study was conducted to identify the toxicity of Malaysian herbs towards the brine shrimp lethality assay. Eleven methanolic herbal extracts were evaluated with concentrations of 0.78, 1.56, 3.13, 6.25, 12.50, 25, 50, and 100 mg mL-1 against the brine shrimp lethality assay. The highest brine sh...

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Main Author: Abdul Rahim, Rozita Hanim
Format: Thesis
Language:English
Published: 2005
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Online Access:https://ir.uitm.edu.my/id/eprint/99085/1/99085.PDF
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spelling my-uitm-ir.990852024-07-24T03:54:29Z Evaluation of Malaysian herbs on artemia salina toxicity assay / Rozita Hanim Abdul Rahim 2005 Abdul Rahim, Rozita Hanim RM Therapeutics. Pharmacology RS Pharmacy and materia medica This study was conducted to identify the toxicity of Malaysian herbs towards the brine shrimp lethality assay. Eleven methanolic herbal extracts were evaluated with concentrations of 0.78, 1.56, 3.13, 6.25, 12.50, 25, 50, and 100 mg mL-1 against the brine shrimp lethality assay. The highest brine shrimp toxicity (IC50 = 0.02 mg mL-1) was observed in "Species 8". Meanwhile, "Species 4" has the lowest brine shrimp toxicity (IC50 = 30.40 mg mL-1) in this study. "Species 7" and "Species 9" did not exhibit lethality towards the brine shrimp for all concentration evaluated. From eleven methanolic herbal extracts that were evaluated, only nine methanolic herbal extracts exhibited toxicity towards the brine shrimp lethality assay with IC50 values ranging from 0.02 to 30.40 mg mL-1. There were "Species l ", "Species 2", "Species 3", "Species 4", "Species 5", "Species 6", "Species 8", "Species 10" and "Species 11" with IC50 values of 19.47 mg mL-1 , 16.20 mg mL-1, 11.14 mg mL-1, 30.40 mg mL-1, 8.02 mg m 2005 Thesis https://ir.uitm.edu.my/id/eprint/99085/ https://ir.uitm.edu.my/id/eprint/99085/1/99085.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Yan, Choo Chee
institution Universiti Teknologi MARA
collection UiTM Institutional Repository
language English
advisor Yan, Choo Chee
topic RM Therapeutics
Pharmacology
RS Pharmacy and materia medica
spellingShingle RM Therapeutics
Pharmacology
RS Pharmacy and materia medica
Abdul Rahim, Rozita Hanim
Evaluation of Malaysian herbs on artemia salina toxicity assay / Rozita Hanim Abdul Rahim
description This study was conducted to identify the toxicity of Malaysian herbs towards the brine shrimp lethality assay. Eleven methanolic herbal extracts were evaluated with concentrations of 0.78, 1.56, 3.13, 6.25, 12.50, 25, 50, and 100 mg mL-1 against the brine shrimp lethality assay. The highest brine shrimp toxicity (IC50 = 0.02 mg mL-1) was observed in "Species 8". Meanwhile, "Species 4" has the lowest brine shrimp toxicity (IC50 = 30.40 mg mL-1) in this study. "Species 7" and "Species 9" did not exhibit lethality towards the brine shrimp for all concentration evaluated. From eleven methanolic herbal extracts that were evaluated, only nine methanolic herbal extracts exhibited toxicity towards the brine shrimp lethality assay with IC50 values ranging from 0.02 to 30.40 mg mL-1. There were "Species l ", "Species 2", "Species 3", "Species 4", "Species 5", "Species 6", "Species 8", "Species 10" and "Species 11" with IC50 values of 19.47 mg mL-1 , 16.20 mg mL-1, 11.14 mg mL-1, 30.40 mg mL-1, 8.02 mg m
format Thesis
qualification_level Bachelor degree
author Abdul Rahim, Rozita Hanim
author_facet Abdul Rahim, Rozita Hanim
author_sort Abdul Rahim, Rozita Hanim
title Evaluation of Malaysian herbs on artemia salina toxicity assay / Rozita Hanim Abdul Rahim
title_short Evaluation of Malaysian herbs on artemia salina toxicity assay / Rozita Hanim Abdul Rahim
title_full Evaluation of Malaysian herbs on artemia salina toxicity assay / Rozita Hanim Abdul Rahim
title_fullStr Evaluation of Malaysian herbs on artemia salina toxicity assay / Rozita Hanim Abdul Rahim
title_full_unstemmed Evaluation of Malaysian herbs on artemia salina toxicity assay / Rozita Hanim Abdul Rahim
title_sort evaluation of malaysian herbs on artemia salina toxicity assay / rozita hanim abdul rahim
granting_institution Universiti Teknologi MARA (Kampus Puncak Alam)
granting_department Faculty of Pharmacy
publishDate 2005
url https://ir.uitm.edu.my/id/eprint/99085/1/99085.PDF
_version_ 1811768980475478016