The tack modifying effects of citrate compounds on hydroxypropylmethylcellulose solution / Nur Mariana Ayub

The study sets to determine the effects of plasticizers on the tackiness of the hydroxypropylmethylcellulose (HPMC) solution. The HPMC solution, without or with the incorporation of plasticizers, was subjected to the tack measurement by using the torsion balance at 30°C. The plasticizers used were c...

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Main Author:	Ayub, Nur Mariana
Format:	Thesis
Language:	English
Published:	2006
Subjects:	RM Therapeutics Pharmacology RS Pharmacy and materia medica
Online Access:	https://ir.uitm.edu.my/id/eprint/99086/1/99086.PDF
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id	my-uitm-ir.99086
record_format	uketd_dc
spelling	my-uitm-ir.990862024-07-24T03:54:26Z The tack modifying effects of citrate compounds on hydroxypropylmethylcellulose solution / Nur Mariana Ayub 2006 Ayub, Nur Mariana RM Therapeutics. Pharmacology RS Pharmacy and materia medica The study sets to determine the effects of plasticizers on the tackiness of the hydroxypropylmethylcellulose (HPMC) solution. The HPMC solution, without or with the incorporation of plasticizers, was subjected to the tack measurement by using the torsion balance at 30°C. The plasticizers used were citric acid, triacetin, triethyl citrate and trisodium citrate. The blank HPMC and plasticizer loaded HPMC solution were subjected to molecular spectroscopy analysis by mean of Fourier Transform Infra-red Analysis. All plasticizers could modify the tack of 0.5% w/w HPMC solution. Nonetheless, none of the plasticizers could reduce the tack of HPMC solution to a value lower than that of the blank solution. The tack of plasticizer-added HPMC solution was mediated from the interaction between the polymer and/or plasticizer molecules, typically via the 0-H functional groups. Citric acid, triacetin, triethyl citrate and trisodium citrate could not effectively reduce the tack force of 0.5% w/w HPMC solutions. 2006 Thesis https://ir.uitm.edu.my/id/eprint/99086/ https://ir.uitm.edu.my/id/eprint/99086/1/99086.PDF text en public diploma Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Wui, Wong Tin
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Wui, Wong Tin
topic	RM Therapeutics Pharmacology RS Pharmacy and materia medica
spellingShingle	RM Therapeutics Pharmacology RS Pharmacy and materia medica Ayub, Nur Mariana The tack modifying effects of citrate compounds on hydroxypropylmethylcellulose solution / Nur Mariana Ayub
description	The study sets to determine the effects of plasticizers on the tackiness of the hydroxypropylmethylcellulose (HPMC) solution. The HPMC solution, without or with the incorporation of plasticizers, was subjected to the tack measurement by using the torsion balance at 30°C. The plasticizers used were citric acid, triacetin, triethyl citrate and trisodium citrate. The blank HPMC and plasticizer loaded HPMC solution were subjected to molecular spectroscopy analysis by mean of Fourier Transform Infra-red Analysis. All plasticizers could modify the tack of 0.5% w/w HPMC solution. Nonetheless, none of the plasticizers could reduce the tack of HPMC solution to a value lower than that of the blank solution. The tack of plasticizer-added HPMC solution was mediated from the interaction between the polymer and/or plasticizer molecules, typically via the 0-H functional groups. Citric acid, triacetin, triethyl citrate and trisodium citrate could not effectively reduce the tack force of 0.5% w/w HPMC solutions.
format	Thesis
qualification_level	diploma
author	Ayub, Nur Mariana
author_facet	Ayub, Nur Mariana
author_sort	Ayub, Nur Mariana
title	The tack modifying effects of citrate compounds on hydroxypropylmethylcellulose solution / Nur Mariana Ayub
title_short	The tack modifying effects of citrate compounds on hydroxypropylmethylcellulose solution / Nur Mariana Ayub
title_full	The tack modifying effects of citrate compounds on hydroxypropylmethylcellulose solution / Nur Mariana Ayub
title_fullStr	The tack modifying effects of citrate compounds on hydroxypropylmethylcellulose solution / Nur Mariana Ayub
title_full_unstemmed	The tack modifying effects of citrate compounds on hydroxypropylmethylcellulose solution / Nur Mariana Ayub
title_sort	tack modifying effects of citrate compounds on hydroxypropylmethylcellulose solution / nur mariana ayub
granting_institution	Universiti Teknologi MARA (Kampus Puncak Alam)
granting_department	Faculty of Pharmacy
publishDate	2006
url	https://ir.uitm.edu.my/id/eprint/99086/1/99086.PDF
_version_	1811768980723990528

The tack modifying effects of citrate compounds on hydroxypropylmethylcellulose solution / Nur Mariana Ayub

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