Chemical constituents and biological activities of syzygium filiforme var. filiforme stem bark / Mohd Hafiz Ahmad

The stem bark of syzygium filiforme var. filiforme from family of myrtaceae was investigated for its chemical constituents and biological activities. About 3 kg of the stem bark was extracted successively using solvent of different polarity. Various chromatographic methods were used to isolate and p...

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Main Author: Ahmad, Mohd Hafiz
Format: Thesis
Language:English
Published: 2015
Online Access:https://ir.uitm.edu.my/id/eprint/99091/1/99091.pdf
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spelling my-uitm-ir.990912024-09-28T15:55:54Z Chemical constituents and biological activities of syzygium filiforme var. filiforme stem bark / Mohd Hafiz Ahmad 2015 Ahmad, Mohd Hafiz The stem bark of syzygium filiforme var. filiforme from family of myrtaceae was investigated for its chemical constituents and biological activities. About 3 kg of the stem bark was extracted successively using solvent of different polarity. Various chromatographic methods were used to isolate and purify compounds from dichloromethane and methanol extracts such as vacuum liquid chromatography, glass column, centrifugal thin layer chromatography, thin layer chromatography and preparative thin layer chromatography. This study resulted in the isolation of five pentacyclic triterpenoids and two phytosterols which are 2a, 3/?, 23-trihydroxyolean12-en-28-oic acid (arjunolic acid, SF1), 2a, 3/?-dihydroxylup-20(29)-en-28-oic acid (alphitolic acid, SF2), 3y#-hydroxylup-20(29)-en-28-oic acid (betulinic acid, SF3), 3phydroxyurs-12-en-28-oic acid (ursolic acid, SF4), ursolic acid 3-methyl ester (SF5), ^-sitosterol (SF6) and stigmasterol (SF7). 2015 Thesis https://ir.uitm.edu.my/id/eprint/99091/ https://ir.uitm.edu.my/id/eprint/99091/1/99091.pdf text en public masters Universiti Teknologi MARA (UiTM) Faculty of Applied Sciences Ismail, Nor Hadiani
institution Universiti Teknologi MARA
collection UiTM Institutional Repository
language English
advisor Ismail, Nor Hadiani
description The stem bark of syzygium filiforme var. filiforme from family of myrtaceae was investigated for its chemical constituents and biological activities. About 3 kg of the stem bark was extracted successively using solvent of different polarity. Various chromatographic methods were used to isolate and purify compounds from dichloromethane and methanol extracts such as vacuum liquid chromatography, glass column, centrifugal thin layer chromatography, thin layer chromatography and preparative thin layer chromatography. This study resulted in the isolation of five pentacyclic triterpenoids and two phytosterols which are 2a, 3/?, 23-trihydroxyolean12-en-28-oic acid (arjunolic acid, SF1), 2a, 3/?-dihydroxylup-20(29)-en-28-oic acid (alphitolic acid, SF2), 3y#-hydroxylup-20(29)-en-28-oic acid (betulinic acid, SF3), 3phydroxyurs-12-en-28-oic acid (ursolic acid, SF4), ursolic acid 3-methyl ester (SF5), ^-sitosterol (SF6) and stigmasterol (SF7).
format Thesis
qualification_level Master's degree
author Ahmad, Mohd Hafiz
spellingShingle Ahmad, Mohd Hafiz
Chemical constituents and biological activities of syzygium filiforme var. filiforme stem bark / Mohd Hafiz Ahmad
author_facet Ahmad, Mohd Hafiz
author_sort Ahmad, Mohd Hafiz
title Chemical constituents and biological activities of syzygium filiforme var. filiforme stem bark / Mohd Hafiz Ahmad
title_short Chemical constituents and biological activities of syzygium filiforme var. filiforme stem bark / Mohd Hafiz Ahmad
title_full Chemical constituents and biological activities of syzygium filiforme var. filiforme stem bark / Mohd Hafiz Ahmad
title_fullStr Chemical constituents and biological activities of syzygium filiforme var. filiforme stem bark / Mohd Hafiz Ahmad
title_full_unstemmed Chemical constituents and biological activities of syzygium filiforme var. filiforme stem bark / Mohd Hafiz Ahmad
title_sort chemical constituents and biological activities of syzygium filiforme var. filiforme stem bark / mohd hafiz ahmad
granting_institution Universiti Teknologi MARA (UiTM)
granting_department Faculty of Applied Sciences
publishDate 2015
url https://ir.uitm.edu.my/id/eprint/99091/1/99091.pdf
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