Direct one-step PCR reaction for detection of CYP2D6 poor metaboliser / Noor Nabila Ajmi

CYP2D6 is a highly polymorphic enzyme that mediates the metabolism of many currently prescribed drugs. Genetic variability within CYP2D6 results in poor (PM), intermediate (IM), extensive (EM) and ultra-rapid metabolisers (UM) of CYP2D6 substrates with PMs are at higher risk than other metabolisers...

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Bibliographic Details
Main Author: Ajmi, Noor Nabila
Format: Thesis
Language:English
Published: 2006
Subjects:
DNA
Online Access:https://ir.uitm.edu.my/id/eprint/99129/1/99129.PDF
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