Effects of phosphine ligands on heck reaction / Nur Nadia Zubir
The use of phosphine ligands in Pd-catalyzed Heck reactions between an aryl iodide and a styrene was investigated. One phosphine ligand is the P(o-Tol)3 and the other is a phosphine ligannd that has been precomplexed with Pd, forming the preformed catalyst, Pd(PPh3)4. Two reactions using these ligan...
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| Format: | Thesis |
| Language: | English |
| Published: |
2007
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| Subjects: | |
| Online Access: | https://ir.uitm.edu.my/id/eprint/99591/1/99591.PDF |
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| Summary: | The use of phosphine ligands in Pd-catalyzed Heck reactions between an aryl iodide and a styrene was investigated. One phosphine ligand is the P(o-Tol)3 and the other is a phosphine ligannd that has been precomplexed with Pd, forming the preformed catalyst, Pd(PPh3)4. Two reactions using these ligands ( one in each reaction) were made for the synthesis of 3,4-dimethoxy-12-benzyloxystilbene and the resulting reaction time and yield for the two reactions using two different ligands were compared. The reaction using P(o-Tol)3 took 22 hours and gave 9.83% yield while the preformed catalyst [Pd(PPh3)4] took 12 hours and gave 16.4% yield. |
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