Effects of phosphine ligands on heck reaction / Nur Nadia Zubir
The use of phosphine ligands in Pd-catalyzed Heck reactions between an aryl iodide and a styrene was investigated. One phosphine ligand is the P(o-Tol)3 and the other is a phosphine ligannd that has been precomplexed with Pd, forming the preformed catalyst, Pd(PPh3)4. Two reactions using these ligan...
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2007
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| Online Access: | https://ir.uitm.edu.my/id/eprint/99591/1/99591.PDF |
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my-uitm-ir.995912024-08-02T04:07:55Z Effects of phosphine ligands on heck reaction / Nur Nadia Zubir 2007 Zubir, Nur Nadia RM Therapeutics. Pharmacology RS Pharmacy and materia medica The use of phosphine ligands in Pd-catalyzed Heck reactions between an aryl iodide and a styrene was investigated. One phosphine ligand is the P(o-Tol)3 and the other is a phosphine ligannd that has been precomplexed with Pd, forming the preformed catalyst, Pd(PPh3)4. Two reactions using these ligands ( one in each reaction) were made for the synthesis of 3,4-dimethoxy-12-benzyloxystilbene and the resulting reaction time and yield for the two reactions using two different ligands were compared. The reaction using P(o-Tol)3 took 22 hours and gave 9.83% yield while the preformed catalyst [Pd(PPh3)4] took 12 hours and gave 16.4% yield. 2007 Thesis https://ir.uitm.edu.my/id/eprint/99591/ https://ir.uitm.edu.my/id/eprint/99591/1/99591.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Feroz, Fareeda |
| institution |
Universiti Teknologi MARA |
| collection |
UiTM Institutional Repository |
| language |
English |
| advisor |
Feroz, Fareeda |
| topic |
RM Therapeutics Pharmacology RS Pharmacy and materia medica |
| spellingShingle |
RM Therapeutics Pharmacology RS Pharmacy and materia medica Zubir, Nur Nadia Effects of phosphine ligands on heck reaction / Nur Nadia Zubir |
| description |
The use of phosphine ligands in Pd-catalyzed Heck reactions between an aryl iodide and a styrene was investigated. One phosphine ligand is the P(o-Tol)3 and the other is a phosphine ligannd that has been precomplexed with Pd, forming the preformed catalyst, Pd(PPh3)4. Two reactions using these ligands ( one in each reaction) were made for the synthesis of 3,4-dimethoxy-12-benzyloxystilbene and the resulting reaction time and yield for the two reactions using two different ligands were compared. The reaction using P(o-Tol)3 took 22 hours and gave 9.83% yield while the preformed catalyst [Pd(PPh3)4] took 12 hours and gave 16.4% yield. |
| format |
Thesis |
| qualification_level |
Bachelor degree |
| author |
Zubir, Nur Nadia |
| author_facet |
Zubir, Nur Nadia |
| author_sort |
Zubir, Nur Nadia |
| title |
Effects of phosphine ligands on heck reaction / Nur Nadia Zubir |
| title_short |
Effects of phosphine ligands on heck reaction / Nur Nadia Zubir |
| title_full |
Effects of phosphine ligands on heck reaction / Nur Nadia Zubir |
| title_fullStr |
Effects of phosphine ligands on heck reaction / Nur Nadia Zubir |
| title_full_unstemmed |
Effects of phosphine ligands on heck reaction / Nur Nadia Zubir |
| title_sort |
effects of phosphine ligands on heck reaction / nur nadia zubir |
| granting_institution |
Universiti Teknologi MARA (Kampus Puncak Alam) |
| granting_department |
Faculty of Pharmacy |
| publishDate |
2007 |
| url |
https://ir.uitm.edu.my/id/eprint/99591/1/99591.PDF |
| _version_ |
1811769004219432960 |