Effects of herbicide residues on reproduction and thyroid function / Mohd Hadafi Mohd Yasim
This study was carried out with a view to investigate the effects of residual doses of herbicide mixtures on endocrine and reproductive function in male SD rats. Animals were exposed to MRL, MTD and high doses from PND 23 to PND 53. Results show that increasing dose of herbicidal mixture of paraquat...
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| Main Author: | |
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| Format: | Thesis |
| Language: | English |
| Published: |
2007
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| Subjects: | |
| Online Access: | https://ir.uitm.edu.my/id/eprint/99632/1/99632.PDF |
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| Summary: | This study was carried out with a view to investigate the effects of residual doses of herbicide mixtures on endocrine and reproductive function in male SD rats. Animals were exposed to MRL, MTD and high doses from PND 23 to PND 53. Results show that increasing dose of herbicidal mixture of paraquat, 2,4-dichloridephenoxyacetic (2,4-D), glyphosate, and glufosinate delayed puberty in SD rats by 0.4 ± 0.1 (MRL), 1.0 ± 0.5 (MTD), and 4.4 ± 0.3 (high dose) days. These delays in sexual maturation were accompanied by significant changes in body weight, size of reproductive organs and non-reproductive organ and by alteration in natural hormone levels. |
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