Effects of herbicide residues on reproduction and thyroid function / Mohd Hadafi Mohd Yasim

This study was carried out with a view to investigate the effects of residual doses of herbicide mixtures on endocrine and reproductive function in male SD rats. Animals were exposed to MRL, MTD and high doses from PND 23 to PND 53. Results show that increasing dose of herbicidal mixture of paraquat...

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Main Author: Mohd Yasim, Mohd Hadafi
Format: Thesis
Language:English
Published: 2007
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Online Access:https://ir.uitm.edu.my/id/eprint/99632/1/99632.PDF
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spelling my-uitm-ir.996322024-08-01T22:46:36Z Effects of herbicide residues on reproduction and thyroid function / Mohd Hadafi Mohd Yasim 2007 Mohd Yasim, Mohd Hadafi RM Therapeutics. Pharmacology RS Pharmacy and materia medica This study was carried out with a view to investigate the effects of residual doses of herbicide mixtures on endocrine and reproductive function in male SD rats. Animals were exposed to MRL, MTD and high doses from PND 23 to PND 53. Results show that increasing dose of herbicidal mixture of paraquat, 2,4-dichloridephenoxyacetic (2,4-D), glyphosate, and glufosinate delayed puberty in SD rats by 0.4 ± 0.1 (MRL), 1.0 ± 0.5 (MTD), and 4.4 ± 0.3 (high dose) days. These delays in sexual maturation were accompanied by significant changes in body weight, size of reproductive organs and non-reproductive organ and by alteration in natural hormone levels. 2007 Thesis https://ir.uitm.edu.my/id/eprint/99632/ https://ir.uitm.edu.my/id/eprint/99632/1/99632.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Iguegbe, Aloysius Umelo
institution Universiti Teknologi MARA
collection UiTM Institutional Repository
language English
advisor Iguegbe, Aloysius Umelo
topic RM Therapeutics
Pharmacology
RS Pharmacy and materia medica
spellingShingle RM Therapeutics
Pharmacology
RS Pharmacy and materia medica
Mohd Yasim, Mohd Hadafi
Effects of herbicide residues on reproduction and thyroid function / Mohd Hadafi Mohd Yasim
description This study was carried out with a view to investigate the effects of residual doses of herbicide mixtures on endocrine and reproductive function in male SD rats. Animals were exposed to MRL, MTD and high doses from PND 23 to PND 53. Results show that increasing dose of herbicidal mixture of paraquat, 2,4-dichloridephenoxyacetic (2,4-D), glyphosate, and glufosinate delayed puberty in SD rats by 0.4 ± 0.1 (MRL), 1.0 ± 0.5 (MTD), and 4.4 ± 0.3 (high dose) days. These delays in sexual maturation were accompanied by significant changes in body weight, size of reproductive organs and non-reproductive organ and by alteration in natural hormone levels.
format Thesis
qualification_level Bachelor degree
author Mohd Yasim, Mohd Hadafi
author_facet Mohd Yasim, Mohd Hadafi
author_sort Mohd Yasim, Mohd Hadafi
title Effects of herbicide residues on reproduction and thyroid function / Mohd Hadafi Mohd Yasim
title_short Effects of herbicide residues on reproduction and thyroid function / Mohd Hadafi Mohd Yasim
title_full Effects of herbicide residues on reproduction and thyroid function / Mohd Hadafi Mohd Yasim
title_fullStr Effects of herbicide residues on reproduction and thyroid function / Mohd Hadafi Mohd Yasim
title_full_unstemmed Effects of herbicide residues on reproduction and thyroid function / Mohd Hadafi Mohd Yasim
title_sort effects of herbicide residues on reproduction and thyroid function / mohd hadafi mohd yasim
granting_institution Universiti Teknologi MARA (Kampus Puncak Alam)
granting_department Faculty of Pharmacy
publishDate 2007
url https://ir.uitm.edu.my/id/eprint/99632/1/99632.PDF
_version_ 1811769010862161920