Effect of nicotine on the estrous cycle of female rat / Muhd Hilmi Mohtar

The prevalence of smoking among Malaysian adults aged 15 years and above had increased from 21 % in 1985 to 31 % in 2000. Some 49% of all adult male and 5% of all females are now current smokers. Due largely to population increase, the number of smokers will continue to rise. (Tobacco CPG Malaysia-N...

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Main Author: Mohtar, Muhd Hilmi
Format: Thesis
Language:English
Published: 2007
Subjects:
Online Access:https://ir.uitm.edu.my/id/eprint/99866/1/99866.PDF
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spelling my-uitm-ir.998662024-08-06T18:15:34Z Effect of nicotine on the estrous cycle of female rat / Muhd Hilmi Mohtar 2007 Mohtar, Muhd Hilmi RM Therapeutics. Pharmacology RS Pharmacy and materia medica The prevalence of smoking among Malaysian adults aged 15 years and above had increased from 21 % in 1985 to 31 % in 2000. Some 49% of all adult male and 5% of all females are now current smokers. Due largely to population increase, the number of smokers will continue to rise. (Tobacco CPG Malaysia-New 2003). Hazards of smoking to health is a well known fact, but the number of smokers are still on the increasing trend. Based on the claim made that smoking has adverse reproduction outcomes in women such as infertility, younger age of menopause and menstrual disorder, this research study was conducted using nicotine, which is one of the chemicals present in tobacco product that have effect on physiological system of human. The effect of nicotine on estrous cycle of rats was studied. The method used was through observation of cells present after vaginal smear for duration of 16 days. Result of the study showed that nicotine did prolong the length of the mean estrous cycle from 4.38 days in the controlled samples to 5.54 days in the samples that was injected subcutaneously with nicotine. 2007 Thesis https://ir.uitm.edu.my/id/eprint/99866/ https://ir.uitm.edu.my/id/eprint/99866/1/99866.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Nordin, Massita
institution Universiti Teknologi MARA
collection UiTM Institutional Repository
language English
advisor Nordin, Massita
topic RM Therapeutics
Pharmacology
RS Pharmacy and materia medica
spellingShingle RM Therapeutics
Pharmacology
RS Pharmacy and materia medica
Mohtar, Muhd Hilmi
Effect of nicotine on the estrous cycle of female rat / Muhd Hilmi Mohtar
description The prevalence of smoking among Malaysian adults aged 15 years and above had increased from 21 % in 1985 to 31 % in 2000. Some 49% of all adult male and 5% of all females are now current smokers. Due largely to population increase, the number of smokers will continue to rise. (Tobacco CPG Malaysia-New 2003). Hazards of smoking to health is a well known fact, but the number of smokers are still on the increasing trend. Based on the claim made that smoking has adverse reproduction outcomes in women such as infertility, younger age of menopause and menstrual disorder, this research study was conducted using nicotine, which is one of the chemicals present in tobacco product that have effect on physiological system of human. The effect of nicotine on estrous cycle of rats was studied. The method used was through observation of cells present after vaginal smear for duration of 16 days. Result of the study showed that nicotine did prolong the length of the mean estrous cycle from 4.38 days in the controlled samples to 5.54 days in the samples that was injected subcutaneously with nicotine.
format Thesis
qualification_level Bachelor degree
author Mohtar, Muhd Hilmi
author_facet Mohtar, Muhd Hilmi
author_sort Mohtar, Muhd Hilmi
title Effect of nicotine on the estrous cycle of female rat / Muhd Hilmi Mohtar
title_short Effect of nicotine on the estrous cycle of female rat / Muhd Hilmi Mohtar
title_full Effect of nicotine on the estrous cycle of female rat / Muhd Hilmi Mohtar
title_fullStr Effect of nicotine on the estrous cycle of female rat / Muhd Hilmi Mohtar
title_full_unstemmed Effect of nicotine on the estrous cycle of female rat / Muhd Hilmi Mohtar
title_sort effect of nicotine on the estrous cycle of female rat / muhd hilmi mohtar
granting_institution Universiti Teknologi MARA (Kampus Puncak Alam)
granting_department Faculty of Pharmacy
publishDate 2007
url https://ir.uitm.edu.my/id/eprint/99866/1/99866.PDF
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