Formulation and evaluation of rice bran oil nanoemulsion for cosmetic application by using sucrose monoester / Siti Syahirah Md Radzi

Nanoemulsions are a class of emulsions with fine droplet size in the range of 20-500nm. Nanoemulsions are not thermodynamically stable and because of that their characteristics will depend on the preparation method. The aim of this study is to investigate the effect of formulation and preparation va...

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Main Author:	Md Radzi, Siti Syahirah
Format:	Thesis
Language:	English
Published:	2007
Subjects:	RM Therapeutics Pharmacology RS Pharmacy and materia medica
Online Access:	https://ir.uitm.edu.my/id/eprint/99878/1/99878.PDF
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id	my-uitm-ir.99878
record_format	uketd_dc
spelling	my-uitm-ir.998782024-08-06T17:58:42Z Formulation and evaluation of rice bran oil nanoemulsion for cosmetic application by using sucrose monoester / Siti Syahirah Md Radzi 2007 Md Radzi, Siti Syahirah RM Therapeutics. Pharmacology RS Pharmacy and materia medica Nanoemulsions are a class of emulsions with fine droplet size in the range of 20-500nm. Nanoemulsions are not thermodynamically stable and because of that their characteristics will depend on the preparation method. The aim of this study is to investigate the effect of formulation and preparation variables of nanophase gel as pre-nanoemulsion over nanoemulsion properties. Pre nanoemulsion formulation was first developed by varying sucrose monoester, glycerol/water (8:2) and safflower oil composition to form cubical liquid crystalline system or nanophase gel. Then an emulsion in nano droplet size was produced by the mixing of pre-nanoemulsion with distilled water under gentle and agitation. The effects of different mechanical energy on droplet size and stability of nanoemulsion were then determined with respect to the variation of sucrose monoester and safflower oil composition. Pre-nanoemulsion formulation uses sucrose monoester combination produces smaller droplet size. However, pre-nanoemulsion formulation uses single sucrose monoester unable to produce nanoemulsion as it may separate after promote to the water. In this study, there was no significant different in particles size in terms of using different mechanical energy which were homogenizer and stirrer. The main mechanism of this nanoemulsion breakdown by using high energy emulsification method might be due to coalescence phenomenon. In addition, destabilization of nanoemulsion in long term process could be attributed to Ostwald ripening. 2007 Thesis https://ir.uitm.edu.my/id/eprint/99878/ https://ir.uitm.edu.my/id/eprint/99878/1/99878.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Bustami Effendi, Tommy Julianto
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Bustami Effendi, Tommy Julianto
topic	RM Therapeutics Pharmacology RS Pharmacy and materia medica
spellingShingle	RM Therapeutics Pharmacology RS Pharmacy and materia medica Md Radzi, Siti Syahirah Formulation and evaluation of rice bran oil nanoemulsion for cosmetic application by using sucrose monoester / Siti Syahirah Md Radzi
description	Nanoemulsions are a class of emulsions with fine droplet size in the range of 20-500nm. Nanoemulsions are not thermodynamically stable and because of that their characteristics will depend on the preparation method. The aim of this study is to investigate the effect of formulation and preparation variables of nanophase gel as pre-nanoemulsion over nanoemulsion properties. Pre nanoemulsion formulation was first developed by varying sucrose monoester, glycerol/water (8:2) and safflower oil composition to form cubical liquid crystalline system or nanophase gel. Then an emulsion in nano droplet size was produced by the mixing of pre-nanoemulsion with distilled water under gentle and agitation. The effects of different mechanical energy on droplet size and stability of nanoemulsion were then determined with respect to the variation of sucrose monoester and safflower oil composition. Pre-nanoemulsion formulation uses sucrose monoester combination produces smaller droplet size. However, pre-nanoemulsion formulation uses single sucrose monoester unable to produce nanoemulsion as it may separate after promote to the water. In this study, there was no significant different in particles size in terms of using different mechanical energy which were homogenizer and stirrer. The main mechanism of this nanoemulsion breakdown by using high energy emulsification method might be due to coalescence phenomenon. In addition, destabilization of nanoemulsion in long term process could be attributed to Ostwald ripening.
format	Thesis
qualification_level	Bachelor degree
author	Md Radzi, Siti Syahirah
author_facet	Md Radzi, Siti Syahirah
author_sort	Md Radzi, Siti Syahirah
title	Formulation and evaluation of rice bran oil nanoemulsion for cosmetic application by using sucrose monoester / Siti Syahirah Md Radzi
title_short	Formulation and evaluation of rice bran oil nanoemulsion for cosmetic application by using sucrose monoester / Siti Syahirah Md Radzi
title_full	Formulation and evaluation of rice bran oil nanoemulsion for cosmetic application by using sucrose monoester / Siti Syahirah Md Radzi
title_fullStr	Formulation and evaluation of rice bran oil nanoemulsion for cosmetic application by using sucrose monoester / Siti Syahirah Md Radzi
title_full_unstemmed	Formulation and evaluation of rice bran oil nanoemulsion for cosmetic application by using sucrose monoester / Siti Syahirah Md Radzi
title_sort	formulation and evaluation of rice bran oil nanoemulsion for cosmetic application by using sucrose monoester / siti syahirah md radzi
granting_institution	Universiti Teknologi MARA (Kampus Puncak Alam)
granting_department	Faculty of Pharmacy
publishDate	2007
url	https://ir.uitm.edu.my/id/eprint/99878/1/99878.PDF
_version_	1811769041908400128

Formulation and evaluation of rice bran oil nanoemulsion for cosmetic application by using sucrose monoester / Siti Syahirah Md Radzi

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