Development of a PCR method for detection of UGTJAJ polymorphism / Khairul Muhaimin Othman
Irinotecan is a camptothecin analog with potent antitumor activity resulting from the inhibition of topoisomerase. Dose-limiting toxicity of irinotecan includes severe leukopenia, neutropenia and diarrhea. Genetic polymorphisms of UDP glucuronosyltransferase (UGT) lAl, a key metabolizing enzyme of...
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| Format: | Thesis |
| Language: | English |
| Published: |
2007
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| Subjects: | |
| Online Access: | https://ir.uitm.edu.my/id/eprint/99883/1/99883.PDF |
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