Development of a PCR method for detection of UGTJAJ polymorphism / Khairul Muhaimin Othman
Irinotecan is a camptothecin analog with potent antitumor activity resulting from the inhibition of topoisomerase. Dose-limiting toxicity of irinotecan includes severe leukopenia, neutropenia and diarrhea. Genetic polymorphisms of UDP glucuronosyltransferase (UGT) lAl, a key metabolizing enzyme of...
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Main Author: | Othman, Khairul Muhaimin |
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Format: | Thesis |
Language: | English |
Published: |
2007
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Subjects: | |
Online Access: | https://ir.uitm.edu.my/id/eprint/99883/1/99883.PDF |
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