Effects of peel extract of hylocereus polyrhizus on blood parameter in mice / Nur Eizera herlena Mat Jahaya

Hylocereus polyrhizus, or commonly known as pitahaya, red pitaya and dragon fruit is a fruit originated from Mexico and is currently cultivated around the world. Previous studies have shown that HP possessed nutritional, commercial and medicinal values, especially as an antioxidant source. The objec...

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Main Author:	Mat Jahaya, Nur Eizera Herlena
Format:	Thesis
Language:	English
Published:	2007
Subjects:	RM Therapeutics Pharmacology RS Pharmacy and materia medica
Online Access:	https://ir.uitm.edu.my/id/eprint/99944/1/99944.PDF
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id	my-uitm-ir.99944
record_format	uketd_dc
spelling	my-uitm-ir.999442024-08-07T15:02:36Z Effects of peel extract of hylocereus polyrhizus on blood parameter in mice / Nur Eizera herlena Mat Jahaya 2007 Mat Jahaya, Nur Eizera Herlena RM Therapeutics. Pharmacology RS Pharmacy and materia medica Hylocereus polyrhizus, or commonly known as pitahaya, red pitaya and dragon fruit is a fruit originated from Mexico and is currently cultivated around the world. Previous studies have shown that HP possessed nutritional, commercial and medicinal values, especially as an antioxidant source. The objective of this study was to evaluate and determine the toxicity profile of HP on blood parameters. Mice were divided equally into two groups and were administered either the peel extract of HP (treatment group) or normal saline ( control group). The peel extract of HP was dissolved in normal saline and administered to mice via orogastric gavage method. No mortality and clinical signs of toxicity were observed upon administration of HP in both the acute and subacute toxicity studies. Blood samples were analyzed based on haematological and biochemical properties and expressed as mean ± standard deviation. Blood analysis from 24-hour and 48-hour acute toxicity testing as well as subacute toxicity testing showed that acute exposure to HP peel extract did not affect the blood parameters. It is concluded that acute and subacute exposure to HP did not affect the blood parameters. These results offer a basis for further development of HP extract for use as a natural antioxidant. 2007 Thesis https://ir.uitm.edu.my/id/eprint/99944/ https://ir.uitm.edu.my/id/eprint/99944/1/99944.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Sulong, Adnan
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Sulong, Adnan
topic	RM Therapeutics Pharmacology RS Pharmacy and materia medica
spellingShingle	RM Therapeutics Pharmacology RS Pharmacy and materia medica Mat Jahaya, Nur Eizera Herlena Effects of peel extract of hylocereus polyrhizus on blood parameter in mice / Nur Eizera herlena Mat Jahaya
description	Hylocereus polyrhizus, or commonly known as pitahaya, red pitaya and dragon fruit is a fruit originated from Mexico and is currently cultivated around the world. Previous studies have shown that HP possessed nutritional, commercial and medicinal values, especially as an antioxidant source. The objective of this study was to evaluate and determine the toxicity profile of HP on blood parameters. Mice were divided equally into two groups and were administered either the peel extract of HP (treatment group) or normal saline ( control group). The peel extract of HP was dissolved in normal saline and administered to mice via orogastric gavage method. No mortality and clinical signs of toxicity were observed upon administration of HP in both the acute and subacute toxicity studies. Blood samples were analyzed based on haematological and biochemical properties and expressed as mean ± standard deviation. Blood analysis from 24-hour and 48-hour acute toxicity testing as well as subacute toxicity testing showed that acute exposure to HP peel extract did not affect the blood parameters. It is concluded that acute and subacute exposure to HP did not affect the blood parameters. These results offer a basis for further development of HP extract for use as a natural antioxidant.
format	Thesis
qualification_level	Bachelor degree
author	Mat Jahaya, Nur Eizera Herlena
author_facet	Mat Jahaya, Nur Eizera Herlena
author_sort	Mat Jahaya, Nur Eizera Herlena
title	Effects of peel extract of hylocereus polyrhizus on blood parameter in mice / Nur Eizera herlena Mat Jahaya
title_short	Effects of peel extract of hylocereus polyrhizus on blood parameter in mice / Nur Eizera herlena Mat Jahaya
title_full	Effects of peel extract of hylocereus polyrhizus on blood parameter in mice / Nur Eizera herlena Mat Jahaya
title_fullStr	Effects of peel extract of hylocereus polyrhizus on blood parameter in mice / Nur Eizera herlena Mat Jahaya
title_full_unstemmed	Effects of peel extract of hylocereus polyrhizus on blood parameter in mice / Nur Eizera herlena Mat Jahaya
title_sort	effects of peel extract of hylocereus polyrhizus on blood parameter in mice / nur eizera herlena mat jahaya
granting_institution	Universiti Teknologi MARA (Kampus Puncak Alam)
granting_department	Faculty of Pharmacy
publishDate	2007
url	https://ir.uitm.edu.my/id/eprint/99944/1/99944.PDF
_version_	1811769064282914816

Effects of peel extract of hylocereus polyrhizus on blood parameter in mice / Nur Eizera herlena Mat Jahaya

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