Development of antimicrobial fabrics based on silver and copper nanoparticles

With growing public unease surrounding the extent of microbial infections, there is a demand for antimicrobial materials including antimicrobial textiles. Nanotechnology has provided new solutions for the development of antimicrobial fabrics. In this study, nanoparticles of silver (Ag) and copper (...

Full description

Saved in:

Bibliographic Details
Main Author:	Norashikin, Mat Zain
Format:	Thesis
Language:	English
Published:	2014
Subjects:	TP Chemical technology
Online Access:	http://umpir.ump.edu.my/id/eprint/13502/1/FKKSA%20-%20NORASHIKIN%20MAT%20ZAIN.PDF
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my-ump-ir.13502
record_format	uketd_dc
spelling	my-ump-ir.135022021-08-25T03:35:37Z Development of antimicrobial fabrics based on silver and copper nanoparticles 2014-10 Norashikin, Mat Zain TP Chemical technology With growing public unease surrounding the extent of microbial infections, there is a demand for antimicrobial materials including antimicrobial textiles. Nanotechnology has provided new solutions for the development of antimicrobial fabrics. In this study, nanoparticles of silver (Ag) and copper (Cu) and alloy nanoparticles of Ag and Cu (Ag/Cu) have been synthesized by reduction of their respective nitrates by ascorbic acid, using chitosan as a stabilising agent and microwave heating. UV-vis spectrophotometry indicated the presence of the alloy by a single peak (500 nm) for Ag/Cu nanoparticles, whereas mixtures of Ag and Cu nanoparticles (Ag+Cu) showed two peaks of 420 and 500 nm, corresponding to pure Ag and Cu nanoparticles respectively. Particle size is increased by increasing nitrate concentration and reducing the chitosan concentration; Surface zeta potentials were positive for all the nanoparticles and varied from +27.8 to +33.8 mV. Ag and Cu nanoparticles were shown to be spherical whilst the alloy nanoparticles had an irregular shape. Cu nanoparticles resulted in higher inactivation of bacteria such as Bacillus subtilis (B. subtilis), Escherichia coli (E. coli) and methicillin-resistant Staphylococcus aureus (MRSA) than did Ag nanoparticles at the same concentration. The effect was reversed when tested on nanoparticles of the same mean particle sizee w ith Ag nanoparticles emerging as. more effective. Bacterial inactivation increased with concentration Of chitosan and the metal concentration. The nanoparticles showed a more potent antibacterial effect than did ions of the same metal. B. subtilis was more susceptible than E. co/i which may be due to the differences in their cell walls structure. MRSA proved harder to inactivate than both B. subtilis and E. coli under identical conditions. Antifungal activity was significantly affected by the types of nanoparticles employed. Ag nanoparticles displayed higher inactivation than Cu ones. Alloyed nanoparticles demonstrated the highest inactivation against both bacteria and fungi. This constitutes clear evidence of an antimicrobial synergy between the Ag and Cu. Bacteria and fungi in contact with nanoparticle-impregnated fabrics were revealed by FEGSEM to have taken on ashrunken appearance. Nanoparticle-impregnated fabrics reduced microbial viability by 80-90%, but this decreased in relation to the number of washes the fabric was subjected to and indicated a leached out of the nanoparticles. Pre-treatment of cotton fabrics with tannic acid and citric acid enhanced the durability of the antimicrobial effect when washed and this increased with concentration of the acid. Citric acid treated fabrics showed higher durability than tannic acid treated fabrics. Log reductions of Trichophyton interdigitale (T interdigitale) were lower than those for B. subiilis, E. coli and MRSA at the same test conditions. The combination of nanoparticles with the antifungal drug fluconazole proved effective, and reduced the time necessary to eliminate the T interdigitale than either nanoparticles or fluconazole alone. 2014-10 Thesis http://umpir.ump.edu.my/id/eprint/13502/ http://umpir.ump.edu.my/id/eprint/13502/1/FKKSA%20-%20NORASHIKIN%20MAT%20ZAIN.PDF application/pdf en public phd doctoral Loughborough University Department of Chemical Engineering
institution	Universiti Malaysia Pahang Al-Sultan Abdullah
collection	UMPSA Institutional Repository
language	English
topic	TP Chemical technology
spellingShingle	TP Chemical technology Norashikin, Mat Zain Development of antimicrobial fabrics based on silver and copper nanoparticles
description	With growing public unease surrounding the extent of microbial infections, there is a demand for antimicrobial materials including antimicrobial textiles. Nanotechnology has provided new solutions for the development of antimicrobial fabrics. In this study, nanoparticles of silver (Ag) and copper (Cu) and alloy nanoparticles of Ag and Cu (Ag/Cu) have been synthesized by reduction of their respective nitrates by ascorbic acid, using chitosan as a stabilising agent and microwave heating. UV-vis spectrophotometry indicated the presence of the alloy by a single peak (500 nm) for Ag/Cu nanoparticles, whereas mixtures of Ag and Cu nanoparticles (Ag+Cu) showed two peaks of 420 and 500 nm, corresponding to pure Ag and Cu nanoparticles respectively. Particle size is increased by increasing nitrate concentration and reducing the chitosan concentration; Surface zeta potentials were positive for all the nanoparticles and varied from +27.8 to +33.8 mV. Ag and Cu nanoparticles were shown to be spherical whilst the alloy nanoparticles had an irregular shape. Cu nanoparticles resulted in higher inactivation of bacteria such as Bacillus subtilis (B. subtilis), Escherichia coli (E. coli) and methicillin-resistant Staphylococcus aureus (MRSA) than did Ag nanoparticles at the same concentration. The effect was reversed when tested on nanoparticles of the same mean particle sizee w ith Ag nanoparticles emerging as. more effective. Bacterial inactivation increased with concentration Of chitosan and the metal concentration. The nanoparticles showed a more potent antibacterial effect than did ions of the same metal. B. subtilis was more susceptible than E. co/i which may be due to the differences in their cell walls structure. MRSA proved harder to inactivate than both B. subtilis and E. coli under identical conditions. Antifungal activity was significantly affected by the types of nanoparticles employed. Ag nanoparticles displayed higher inactivation than Cu ones. Alloyed nanoparticles demonstrated the highest inactivation against both bacteria and fungi. This constitutes clear evidence of an antimicrobial synergy between the Ag and Cu. Bacteria and fungi in contact with nanoparticle-impregnated fabrics were revealed by FEGSEM to have taken on ashrunken appearance. Nanoparticle-impregnated fabrics reduced microbial viability by 80-90%, but this decreased in relation to the number of washes the fabric was subjected to and indicated a leached out of the nanoparticles. Pre-treatment of cotton fabrics with tannic acid and citric acid enhanced the durability of the antimicrobial effect when washed and this increased with concentration of the acid. Citric acid treated fabrics showed higher durability than tannic acid treated fabrics. Log reductions of Trichophyton interdigitale (T interdigitale) were lower than those for B. subiilis, E. coli and MRSA at the same test conditions. The combination of nanoparticles with the antifungal drug fluconazole proved effective, and reduced the time necessary to eliminate the T interdigitale than either nanoparticles or fluconazole alone.
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Norashikin, Mat Zain
author_facet	Norashikin, Mat Zain
author_sort	Norashikin, Mat Zain
title	Development of antimicrobial fabrics based on silver and copper nanoparticles
title_short	Development of antimicrobial fabrics based on silver and copper nanoparticles
title_full	Development of antimicrobial fabrics based on silver and copper nanoparticles
title_fullStr	Development of antimicrobial fabrics based on silver and copper nanoparticles
title_full_unstemmed	Development of antimicrobial fabrics based on silver and copper nanoparticles
title_sort	development of antimicrobial fabrics based on silver and copper nanoparticles
granting_institution	Loughborough University
granting_department	Department of Chemical Engineering
publishDate	2014
url	http://umpir.ump.edu.my/id/eprint/13502/1/FKKSA%20-%20NORASHIKIN%20MAT%20ZAIN.PDF
_version_	1783731985445814272

Development of antimicrobial fabrics based on silver and copper nanoparticles

Similar Items