Clinical profile and outcome of children who underwent micturating cystourethrogram: A tertiary hospital experience

Micturating cystourethrogram (MCUG) is the gold standard test for the diagnosis of vesicoureteric reflux (VUR). The study aims to establish the association between the presence ofVUR and renal outcomes. A cross-sectional retrospective study was conducted in children who were referred for MCUG at a t...

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Main Author:	Emie Mading
Format:	Thesis
Language:	English English
Published:	2022
Online Access:	https://eprints.ums.edu.my/id/eprint/35546/1/24%20PAGES.pdf https://eprints.ums.edu.my/id/eprint/35546/2/FULLTEXT.pdf
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spelling	my-ums-ep.355462023-06-06T03:01:05Z Clinical profile and outcome of children who underwent micturating cystourethrogram: A tertiary hospital experience 2022 Emie Mading Micturating cystourethrogram (MCUG) is the gold standard test for the diagnosis of vesicoureteric reflux (VUR). The study aims to establish the association between the presence ofVUR and renal outcomes. A cross-sectional retrospective study was conducted in children who were referred for MCUG at a tertiary centre over a l 0-year period. Baseline characteristic data and the results of renal ultrasound, MCUG, with renal function were compiled and analysed. Fisher Exact tests were used to compare between grade of VUR and renal outcomes. Simple and multiple logistic regressions were used to examine the risk factors that may contribute to the development of VUR. There were 136 children recruited in total of which forty-five were having VUR, (31 [68%] high-grade, 14 [32%] low-grade, respectively). One third (33.3%) were surgically treated, 29 (64.4%) developed chronic kidney disease (CKD), and 18 (40%) developed renal scarring. Children with urinary tract infection (UTT) and hydroureter have 4.19 and 3.40 times the odds of developing VUR respectively. The presence of hydroureter from ultrasound is a strong indicator of underlying VUR and justifies the rationale of requesting for MCUG, especially for those with recurrent UTI. The study failed to demonstrate significant association between the presence ofVUR and complication of renal scarring and CKD. 2022 Thesis https://eprints.ums.edu.my/id/eprint/35546/ https://eprints.ums.edu.my/id/eprint/35546/1/24%20PAGES.pdf text en public https://eprints.ums.edu.my/id/eprint/35546/2/FULLTEXT.pdf text en validuser mphil masters Universiti Sains Malaysia
institution	Universiti Malaysia Sabah
collection	UMS Institutional Repository
language	English English
description	Micturating cystourethrogram (MCUG) is the gold standard test for the diagnosis of vesicoureteric reflux (VUR). The study aims to establish the association between the presence ofVUR and renal outcomes. A cross-sectional retrospective study was conducted in children who were referred for MCUG at a tertiary centre over a l 0-year period. Baseline characteristic data and the results of renal ultrasound, MCUG, with renal function were compiled and analysed. Fisher Exact tests were used to compare between grade of VUR and renal outcomes. Simple and multiple logistic regressions were used to examine the risk factors that may contribute to the development of VUR. There were 136 children recruited in total of which forty-five were having VUR, (31 [68%] high-grade, 14 [32%] low-grade, respectively). One third (33.3%) were surgically treated, 29 (64.4%) developed chronic kidney disease (CKD), and 18 (40%) developed renal scarring. Children with urinary tract infection (UTT) and hydroureter have 4.19 and 3.40 times the odds of developing VUR respectively. The presence of hydroureter from ultrasound is a strong indicator of underlying VUR and justifies the rationale of requesting for MCUG, especially for those with recurrent UTI. The study failed to demonstrate significant association between the presence ofVUR and complication of renal scarring and CKD.
format	Thesis
qualification_name	Master of Philosophy (M.Phil.)
qualification_level	Master's degree
author	Emie Mading
spellingShingle	Emie Mading Clinical profile and outcome of children who underwent micturating cystourethrogram: A tertiary hospital experience
author_facet	Emie Mading
author_sort	Emie Mading
title	Clinical profile and outcome of children who underwent micturating cystourethrogram: A tertiary hospital experience
title_short	Clinical profile and outcome of children who underwent micturating cystourethrogram: A tertiary hospital experience
title_full	Clinical profile and outcome of children who underwent micturating cystourethrogram: A tertiary hospital experience
title_fullStr	Clinical profile and outcome of children who underwent micturating cystourethrogram: A tertiary hospital experience
title_full_unstemmed	Clinical profile and outcome of children who underwent micturating cystourethrogram: A tertiary hospital experience
title_sort	clinical profile and outcome of children who underwent micturating cystourethrogram: a tertiary hospital experience
granting_institution	Universiti Sains Malaysia
publishDate	2022
url	https://eprints.ums.edu.my/id/eprint/35546/1/24%20PAGES.pdf https://eprints.ums.edu.my/id/eprint/35546/2/FULLTEXT.pdf
_version_	1776102891624333312

Clinical profile and outcome of children who underwent micturating cystourethrogram: A tertiary hospital experience

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