Clinical profile and outcome of children who underwent micturating cystourethrogram: A tertiary hospital experience
Micturating cystourethrogram (MCUG) is the gold standard test for the diagnosis of vesicoureteric reflux (VUR). The study aims to establish the association between the presence ofVUR and renal outcomes. A cross-sectional retrospective study was conducted in children who were referred for MCUG at a t...
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2022
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my-ums-ep.355462023-06-06T03:01:05Z Clinical profile and outcome of children who underwent micturating cystourethrogram: A tertiary hospital experience 2022 Emie Mading Micturating cystourethrogram (MCUG) is the gold standard test for the diagnosis of vesicoureteric reflux (VUR). The study aims to establish the association between the presence ofVUR and renal outcomes. A cross-sectional retrospective study was conducted in children who were referred for MCUG at a tertiary centre over a l 0-year period. Baseline characteristic data and the results of renal ultrasound, MCUG, with renal function were compiled and analysed. Fisher Exact tests were used to compare between grade of VUR and renal outcomes. Simple and multiple logistic regressions were used to examine the risk factors that may contribute to the development of VUR. There were 136 children recruited in total of which forty-five were having VUR, (31 [68%] high-grade, 14 [32%] low-grade, respectively). One third (33.3%) were surgically treated, 29 (64.4%) developed chronic kidney disease (CKD), and 18 (40%) developed renal scarring. Children with urinary tract infection (UTT) and hydroureter have 4.19 and 3.40 times the odds of developing VUR respectively. The presence of hydroureter from ultrasound is a strong indicator of underlying VUR and justifies the rationale of requesting for MCUG, especially for those with recurrent UTI. The study failed to demonstrate significant association between the presence ofVUR and complication of renal scarring and CKD. 2022 Thesis https://eprints.ums.edu.my/id/eprint/35546/ https://eprints.ums.edu.my/id/eprint/35546/1/24%20PAGES.pdf text en public https://eprints.ums.edu.my/id/eprint/35546/2/FULLTEXT.pdf text en validuser mphil masters Universiti Sains Malaysia |
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Universiti Malaysia Sabah |
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UMS Institutional Repository |
| language |
English English |
| description |
Micturating cystourethrogram (MCUG) is the gold standard test for the diagnosis of vesicoureteric reflux (VUR). The study aims to establish the association between the presence ofVUR and renal outcomes. A cross-sectional retrospective study was conducted in children who were referred for MCUG at a tertiary centre over a l 0-year period. Baseline characteristic data and the results of renal ultrasound, MCUG, with renal function were compiled and analysed. Fisher Exact tests were used to compare between grade of VUR and renal outcomes. Simple and multiple logistic regressions were used to examine the risk factors that may contribute to the development of VUR. There were 136 children recruited in total of which forty-five were having VUR, (31 [68%] high-grade, 14 [32%] low-grade, respectively). One third (33.3%) were surgically treated, 29 (64.4%) developed chronic kidney disease (CKD), and 18 (40%) developed renal scarring. Children with urinary tract infection (UTT) and hydroureter have 4.19 and 3.40 times the odds of developing VUR respectively. The presence of hydroureter from ultrasound is a strong indicator of underlying VUR and justifies the rationale of requesting for MCUG, especially for those with recurrent UTI. The study failed to demonstrate significant association between the presence ofVUR and complication of renal scarring and CKD. |
| format |
Thesis |
| qualification_name |
Master of Philosophy (M.Phil.) |
| qualification_level |
Master's degree |
| author |
Emie Mading |
| spellingShingle |
Emie Mading Clinical profile and outcome of children who underwent micturating cystourethrogram: A tertiary hospital experience |
| author_facet |
Emie Mading |
| author_sort |
Emie Mading |
| title |
Clinical profile and outcome of children who underwent micturating cystourethrogram: A tertiary hospital experience |
| title_short |
Clinical profile and outcome of children who underwent micturating cystourethrogram: A tertiary hospital experience |
| title_full |
Clinical profile and outcome of children who underwent micturating cystourethrogram: A tertiary hospital experience |
| title_fullStr |
Clinical profile and outcome of children who underwent micturating cystourethrogram: A tertiary hospital experience |
| title_full_unstemmed |
Clinical profile and outcome of children who underwent micturating cystourethrogram: A tertiary hospital experience |
| title_sort |
clinical profile and outcome of children who underwent micturating cystourethrogram: a tertiary hospital experience |
| granting_institution |
Universiti Sains Malaysia |
| publishDate |
2022 |
| url |
https://eprints.ums.edu.my/id/eprint/35546/1/24%20PAGES.pdf https://eprints.ums.edu.my/id/eprint/35546/2/FULLTEXT.pdf |
| _version_ |
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