Expression distribution of cancer stem cell, epithelial to mesenchymal transition and telomerase activity in breast cancer and their association with clinicopathological characteristic

Three novel concepts have been emerged in breast cancer biology: the role of cancer stem cells (CSC) in tumor initiation, and the involvement of an epithelial to mesenchymal transition (EMT) in the invasiveness and metastasis of cancer cells, along with the telomerase role in_ keeping the CSC immort...

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Main Author:	Jaafar Sadeq Makki
Format:	Thesis
Language:	English English
Published:	2014
Subjects:	RC254-282 Neoplasms Tumors Oncology Including cancer and carcinogens
Online Access:	https://eprints.ums.edu.my/id/eprint/37487/1/24%20PAGES.pdf https://eprints.ums.edu.my/id/eprint/37487/2/FULLTEXT.pdf
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spelling	my-ums-ep.374872023-10-13T07:33:15Z Expression distribution of cancer stem cell, epithelial to mesenchymal transition and telomerase activity in breast cancer and their association with clinicopathological characteristic 2014 Jaafar Sadeq Makki RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens Three novel concepts have been emerged in breast cancer biology: the role of cancer stem cells (CSC) in tumor initiation, and the involvement of an epithelial to mesenchymal transition (EMT) in the invasiveness and metastasis of cancer cells, along with the telomerase role in_ keeping the CSC immortal, and avoidino senescence. CSC are a small subpopulation of cells within tumors that initiate the tumor, telomerase is the intracellular enzyme responsible for the elongation of chromosomal telomer during each cell division, while EMT is the loss of epithelial differentiation and gained the mesenchymal phenotype. 2014 Thesis https://eprints.ums.edu.my/id/eprint/37487/ https://eprints.ums.edu.my/id/eprint/37487/1/24%20PAGES.pdf text en public https://eprints.ums.edu.my/id/eprint/37487/2/FULLTEXT.pdf text en validuser phd doctoral Universiti Malaysia Sabah Faculity of medicine and health Sciences
institution	Universiti Malaysia Sabah
collection	UMS Institutional Repository
language	English English
topic	RC254-282 Neoplasms Tumors Oncology Including cancer and carcinogens
spellingShingle	RC254-282 Neoplasms Tumors Oncology Including cancer and carcinogens Jaafar Sadeq Makki Expression distribution of cancer stem cell, epithelial to mesenchymal transition and telomerase activity in breast cancer and their association with clinicopathological characteristic
description	Three novel concepts have been emerged in breast cancer biology: the role of cancer stem cells (CSC) in tumor initiation, and the involvement of an epithelial to mesenchymal transition (EMT) in the invasiveness and metastasis of cancer cells, along with the telomerase role in_ keeping the CSC immortal, and avoidino senescence. CSC are a small subpopulation of cells within tumors that initiate the tumor, telomerase is the intracellular enzyme responsible for the elongation of chromosomal telomer during each cell division, while EMT is the loss of epithelial differentiation and gained the mesenchymal phenotype.
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Jaafar Sadeq Makki
author_facet	Jaafar Sadeq Makki
author_sort	Jaafar Sadeq Makki
title	Expression distribution of cancer stem cell, epithelial to mesenchymal transition and telomerase activity in breast cancer and their association with clinicopathological characteristic
title_short	Expression distribution of cancer stem cell, epithelial to mesenchymal transition and telomerase activity in breast cancer and their association with clinicopathological characteristic
title_full	Expression distribution of cancer stem cell, epithelial to mesenchymal transition and telomerase activity in breast cancer and their association with clinicopathological characteristic
title_fullStr	Expression distribution of cancer stem cell, epithelial to mesenchymal transition and telomerase activity in breast cancer and their association with clinicopathological characteristic
title_full_unstemmed	Expression distribution of cancer stem cell, epithelial to mesenchymal transition and telomerase activity in breast cancer and their association with clinicopathological characteristic
title_sort	expression distribution of cancer stem cell, epithelial to mesenchymal transition and telomerase activity in breast cancer and their association with clinicopathological characteristic
granting_institution	Universiti Malaysia Sabah
granting_department	Faculity of medicine and health Sciences
publishDate	2014
url	https://eprints.ums.edu.my/id/eprint/37487/1/24%20PAGES.pdf https://eprints.ums.edu.my/id/eprint/37487/2/FULLTEXT.pdf
_version_	1783727541537734656

Expression distribution of cancer stem cell, epithelial to mesenchymal transition and telomerase activity in breast cancer and their association with clinicopathological characteristic

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