Glycogen synthase kinase-3β (GSK-3β) inhibitors from soil actinomycetes of Sabah rainforests : screening, purification and identification

Glycogen Synthase Kinase-3 (GSK-3) is a multitasking enzyme involved in various processes cell. It is expressed in two isoforms in mammalian cells; GSK-3α and GSK-3β. Dysregulation of GSK-3 is a causal factor of diseases such as cancer and diabetes. In drug discovery, GSK-3β is usually being targete...

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Bibliographic Details
Main Author: Fauze Mahmud
Format: Thesis
Language:English
English
Published: 2015
Subjects:
Online Access:https://eprints.ums.edu.my/id/eprint/39471/1/24%20PAGES.pdf
https://eprints.ums.edu.my/id/eprint/39471/2/FULLTEXT.pdf
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