Cytotoxic and genotoxic effects of methanolic crude extracts from selected marine sponges collected from Terengganu Island on Acanthamoeba SPP

Cytotoxic and genotoxic effects of methanolic crude extracts from selected marine sponges collected from Terengganu Island on Acanthamoeba SPP

Acanthamoeba is a free-living amoeba but pathogenic to humans, causing a potentially blinding infection of the cornea(keratitis). Keratitis is an important public health problem developing country. Therefore, research on new drugs for the treatment of this infection is still constitutes an importan...

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Main Author: Ida Muryany Md Yasin
Format: Thesis
Language:English
Subjects:
QL 368 .A5 I3 2008
Ida Muryany Md Yasin
Tesis FST 2008
Communicable diseases
Acanthamoeba
Online Access:http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/1002/1/QL%20368%20.A5%20I3%202008%20Abstract.pdf
http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/1002/2/QL%20368%20.A5%20I3%202008%20FullText.pdf
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spelling my-umt-ir.-10022016-03-11T22:09:47Z Cytotoxic and genotoxic effects of methanolic crude extracts from selected marine sponges collected from Terengganu Island on Acanthamoeba SPP Ida Muryany Md Yasin Acanthamoeba is a free-living amoeba but pathogenic to humans, causing a potentially blinding infection of the cornea(keratitis). Keratitis is an important public health problem developing country. Therefore, research on new drugs for the treatment of this infection is still constitutes an important therapeutic demand. The objective of this study were determined the cytotoxic and genotoxic effects of crude extracts of sponges from Aaptos sp., Xestospongia sp. and Halicondria sp. collected from Kapas, Perhentian and Redang Islands, Terengganu on trophozoites of two clinical isolates namely Acanthamoeba castellanii (IMR isolate) and Acanthamoeba sp. (HKL isolate) and one free-living amoeba, Acanthamoeba polyphaga strain 1501/3A (but potential of being pathogenic). Fakulti Sains dan Teknologi 2008-05 Thesis en http://hdl.handle.net/123456789/1002 http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/1002/1/QL%20368%20.A5%20I3%202008%20Abstract.pdf af24bf6e6f1591624a3a6869c04e133f http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/1002/2/QL%20368%20.A5%20I3%202008%20FullText.pdf 1d8a6674aa25c50e8ffa6ae2be113663 http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/1002/3/license.txt ecca7a0b60eabbf88d99eae3662e2d50 http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/1002/4/QL%20368%20.A5%20I3%202008%20Abstract.pdf.txt 042cfae4e8fd92e62ad35555e492fef1 http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/1002/5/QL%20368%20.A5%20I3%202008%20FullText.pdf.txt 6a21d3dd1b58d6d8423fc228c4c8b2e2 QL 368 .A5 I3 2008 Ida Muryany Md Yasin Tesis FST 2008 Communicable diseases Acanthamoeba
institution Universiti Malaysia Terengganu
collection UMT Repository System
language English
topic QL 368 .A5 I3 2008
Ida Muryany Md Yasin
Tesis FST 2008
Communicable diseases
Acanthamoeba
spellingShingle QL 368 .A5 I3 2008
Ida Muryany Md Yasin
Tesis FST 2008
Communicable diseases
Acanthamoeba
Ida Muryany Md Yasin
Cytotoxic and genotoxic effects of methanolic crude extracts from selected marine sponges collected from Terengganu Island on Acanthamoeba SPP
description Acanthamoeba is a free-living amoeba but pathogenic to humans, causing a potentially blinding infection of the cornea(keratitis). Keratitis is an important public health problem developing country. Therefore, research on new drugs for the treatment of this infection is still constitutes an important therapeutic demand. The objective of this study were determined the cytotoxic and genotoxic effects of crude extracts of sponges from Aaptos sp., Xestospongia sp. and Halicondria sp. collected from Kapas, Perhentian and Redang Islands, Terengganu on trophozoites of two clinical isolates namely Acanthamoeba castellanii (IMR isolate) and Acanthamoeba sp. (HKL isolate) and one free-living amoeba, Acanthamoeba polyphaga strain 1501/3A (but potential of being pathogenic).
format Thesis
author Ida Muryany Md Yasin
author_facet Ida Muryany Md Yasin
author_sort Ida Muryany Md Yasin
title Cytotoxic and genotoxic effects of methanolic crude extracts from selected marine sponges collected from Terengganu Island on Acanthamoeba SPP
title_short Cytotoxic and genotoxic effects of methanolic crude extracts from selected marine sponges collected from Terengganu Island on Acanthamoeba SPP
title_full Cytotoxic and genotoxic effects of methanolic crude extracts from selected marine sponges collected from Terengganu Island on Acanthamoeba SPP
title_fullStr Cytotoxic and genotoxic effects of methanolic crude extracts from selected marine sponges collected from Terengganu Island on Acanthamoeba SPP
title_full_unstemmed Cytotoxic and genotoxic effects of methanolic crude extracts from selected marine sponges collected from Terengganu Island on Acanthamoeba SPP
title_sort cytotoxic and genotoxic effects of methanolic crude extracts from selected marine sponges collected from terengganu island on acanthamoeba spp
granting_institution Fakulti Sains dan Teknologi
url http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/1002/1/QL%20368%20.A5%20I3%202008%20Abstract.pdf
http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/1002/2/QL%20368%20.A5%20I3%202008%20FullText.pdf
_version_ 1747835812193501184

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