ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITIES OF Pandanus tectorius ACTIVE FRACTIONS THROUGH NITRIC OXIDE REDUCTIONS

Over the past decades, inflammation has been known as the main root cause for many infectious diseases. There are drugs that are effective against inflammation being used to treat the diseases, which is non-steroidal anti-inflammatory drugs (NSAID) however, they come with side effects to the body...

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Main Author:	NADIAH MADIHAH BINTI RAMLI
Format:	Thesis
Language:	English
Online Access:	http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/16089/1/Abstract.pdf http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/16089/2/Full%20Thesis%20-%20NADIAH%20MADIHAH.pdf
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id	my-umt-ir.-16089
record_format	uketd_dc
spelling	my-umt-ir.-160892022-01-30T06:58:15Z ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITIES OF Pandanus tectorius ACTIVE FRACTIONS THROUGH NITRIC OXIDE REDUCTIONS NADIAH MADIHAH BINTI RAMLI Over the past decades, inflammation has been known as the main root cause for many infectious diseases. There are drugs that are effective against inflammation being used to treat the diseases, which is non-steroidal anti-inflammatory drugs (NSAID) however, they come with side effects to the body. Therefore, in this study, an alternative medicine to treat inflammation has been investigated especially from natural products. Pandanus tectorius fruits have been used as source of food only during war time in few regions in Malaysia but now it is being disregarded. Therefore, in this study, P. tectorius fruit properties as antioxidant and as anti-inflammatory potential agent were carried out. Antioxidant was measured by DPPH method while anti-inflammatory were evaluated based on iNOS inhibitory activity and paw oedema rat model. The crude ethyl acetate (PEF) and methanol (PMF) of P. tectorius showed antioxidant activity at IC50 value of 2.43 and 5.86 mg/ml respectively. UNIVERSITI MALAYSIA TERENGGANU 2020-08 Thesis en http://umt-ir.umt.edu.my:8080/handle/123456789/16089 http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/16089/1/Abstract.pdf ca95d672c3893ad9511b28e0325a40fd http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/16089/2/Full%20Thesis%20-%20NADIAH%20MADIHAH.pdf 8b4210ca4d98b59d0b3016f49d989c41 http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/16089/3/license.txt 8a4605be74aa9ea9d79846c1fba20a33
institution	Universiti Malaysia Terengganu
collection	UMT Repository System
language	English
description	Over the past decades, inflammation has been known as the main root cause for many infectious diseases. There are drugs that are effective against inflammation being used to treat the diseases, which is non-steroidal anti-inflammatory drugs (NSAID) however, they come with side effects to the body. Therefore, in this study, an alternative medicine to treat inflammation has been investigated especially from natural products. Pandanus tectorius fruits have been used as source of food only during war time in few regions in Malaysia but now it is being disregarded. Therefore, in this study, P. tectorius fruit properties as antioxidant and as anti-inflammatory potential agent were carried out. Antioxidant was measured by DPPH method while anti-inflammatory were evaluated based on iNOS inhibitory activity and paw oedema rat model. The crude ethyl acetate (PEF) and methanol (PMF) of P. tectorius showed antioxidant activity at IC50 value of 2.43 and 5.86 mg/ml respectively.
format	Thesis
author	NADIAH MADIHAH BINTI RAMLI
spellingShingle	NADIAH MADIHAH BINTI RAMLI ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITIES OF Pandanus tectorius ACTIVE FRACTIONS THROUGH NITRIC OXIDE REDUCTIONS
author_facet	NADIAH MADIHAH BINTI RAMLI
author_sort	NADIAH MADIHAH BINTI RAMLI
title	ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITIES OF Pandanus tectorius ACTIVE FRACTIONS THROUGH NITRIC OXIDE REDUCTIONS
title_short	ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITIES OF Pandanus tectorius ACTIVE FRACTIONS THROUGH NITRIC OXIDE REDUCTIONS
title_full	ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITIES OF Pandanus tectorius ACTIVE FRACTIONS THROUGH NITRIC OXIDE REDUCTIONS
title_fullStr	ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITIES OF Pandanus tectorius ACTIVE FRACTIONS THROUGH NITRIC OXIDE REDUCTIONS
title_full_unstemmed	ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITIES OF Pandanus tectorius ACTIVE FRACTIONS THROUGH NITRIC OXIDE REDUCTIONS
title_sort	antioxidant and anti-inflammatory activities of pandanus tectorius active fractions through nitric oxide reductions
granting_institution	UNIVERSITI MALAYSIA TERENGGANU
url	http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/16089/1/Abstract.pdf http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/16089/2/Full%20Thesis%20-%20NADIAH%20MADIHAH.pdf
_version_	1747835775497535488

ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITIES OF Pandanus tectorius ACTIVE FRACTIONS THROUGH NITRIC OXIDE REDUCTIONS

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