Effects of honey on factors relating to cardiovascular disease based on in vitro and in vivo studies

Along history, honey has been used not only as a nutrient, but also as a medicine. Honey is rich in phenolic compounds, which act as natural antioxidants and are increasingly popular due to their potential in improving the human health. Thus, this study was designed to analyse some physico-chemic...

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Main Author: Norhayati Binti Abd Hadi
Format: Thesis
Language:English
Online Access:http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/17143/1/Abstract.pdf
http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/17143/2/Norhayati%20Binti%20Abd%20Hadi%20-%20Full%20Thesis.pdf
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spelling my-umt-ir.-171432022-06-21T07:15:38Z Effects of honey on factors relating to cardiovascular disease based on in vitro and in vivo studies Norhayati Binti Abd Hadi Along history, honey has been used not only as a nutrient, but also as a medicine. Honey is rich in phenolic compounds, which act as natural antioxidants and are increasingly popular due to their potential in improving the human health. Thus, this study was designed to analyse some physico-chemical characteristics of two different types of honey, namely honey bee honey (Acacia) and stingless bee honey (Kelulut), to study the anti-inflammatory effects of polyphenols on the atherosclerosis modulation in human umbilical vein endothelial cells (HUVECs) and investigate the effects of these two honey for supplementation in subjects with cardiovascular risk factor. Ash, colour, water activity, viscosity, Brix, moisture, acidity, hidroxymethyl furfural (HMF), diastase activity and sugar analyses of the honey samples were assessed for chemical characterisation. Total phenolic compound, ferric reducing antioxidant capacity (FRAP) and 2, 2-diphenyl-1-picryhydrazyl (DPPH) free radical scavenging activity were measured as antioxidant determinants. Acacia honey in this study showed significantly higher content of colour (redness and yellowness), viscosity, Brix, sugar content, FRAP and total phenolic compared to those of Kelulut honey. The results also showed that Acacia honey had significantly lower content of water activity, moisture, acidity, HMF and diastase activity as compared to Kelulut honey. Universiti Malaysia Terengganu 2019-10 Thesis en http://umt-ir.umt.edu.my:8080/handle/123456789/17143 http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/17143/1/Abstract.pdf 35b63c081616b1e8a60b0b051d26f0b1 http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/17143/2/Norhayati%20Binti%20Abd%20Hadi%20-%20Full%20Thesis.pdf 31b8def3d824e4396599773b8720c0ed http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/17143/3/license.txt 8a4605be74aa9ea9d79846c1fba20a33
institution Universiti Malaysia Terengganu
collection UMT Repository System
language English
description Along history, honey has been used not only as a nutrient, but also as a medicine. Honey is rich in phenolic compounds, which act as natural antioxidants and are increasingly popular due to their potential in improving the human health. Thus, this study was designed to analyse some physico-chemical characteristics of two different types of honey, namely honey bee honey (Acacia) and stingless bee honey (Kelulut), to study the anti-inflammatory effects of polyphenols on the atherosclerosis modulation in human umbilical vein endothelial cells (HUVECs) and investigate the effects of these two honey for supplementation in subjects with cardiovascular risk factor. Ash, colour, water activity, viscosity, Brix, moisture, acidity, hidroxymethyl furfural (HMF), diastase activity and sugar analyses of the honey samples were assessed for chemical characterisation. Total phenolic compound, ferric reducing antioxidant capacity (FRAP) and 2, 2-diphenyl-1-picryhydrazyl (DPPH) free radical scavenging activity were measured as antioxidant determinants. Acacia honey in this study showed significantly higher content of colour (redness and yellowness), viscosity, Brix, sugar content, FRAP and total phenolic compared to those of Kelulut honey. The results also showed that Acacia honey had significantly lower content of water activity, moisture, acidity, HMF and diastase activity as compared to Kelulut honey.
format Thesis
author Norhayati Binti Abd Hadi
spellingShingle Norhayati Binti Abd Hadi
Effects of honey on factors relating to cardiovascular disease based on in vitro and in vivo studies
author_facet Norhayati Binti Abd Hadi
author_sort Norhayati Binti Abd Hadi
title Effects of honey on factors relating to cardiovascular disease based on in vitro and in vivo studies
title_short Effects of honey on factors relating to cardiovascular disease based on in vitro and in vivo studies
title_full Effects of honey on factors relating to cardiovascular disease based on in vitro and in vivo studies
title_fullStr Effects of honey on factors relating to cardiovascular disease based on in vitro and in vivo studies
title_full_unstemmed Effects of honey on factors relating to cardiovascular disease based on in vitro and in vivo studies
title_sort effects of honey on factors relating to cardiovascular disease based on in vitro and in vivo studies
granting_institution Universiti Malaysia Terengganu
url http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/17143/1/Abstract.pdf
http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/17143/2/Norhayati%20Binti%20Abd%20Hadi%20-%20Full%20Thesis.pdf
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