The role of interleukin-8 in inflammatory responses of fish
Interleukin-8, a novel chemotactic cytokine, has been shown to play an important role in activation and recruitment of neutrophils, and thus acts as a traffic controller. This study builds upon the breakthrough in cloning several fish cytokine genes including IL-8. The predicted rainbow trout Oncorh...
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| التنسيق: | أطروحة |
| اللغة: | English |
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| الوصول للمادة أونلاين: | http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/2723/1/QR%20185.8%20.I56%20N6%202006%20Abstract.pdf http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/2723/2/QR%20185.8%20.I56%20N6%202006%20FullText.pdf |
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| الملخص: | Interleukin-8, a novel chemotactic cytokine, has been shown to play an important role in activation and recruitment of neutrophils, and thus acts as a traffic controller. This study builds upon the breakthrough in cloning several fish cytokine genes including IL-8. The predicted rainbow trout Oncorhynchus mykiss mature interleukin-8 peptide has been produced as a recombinant protein in E. coli; interleukin-8 (riL-8a) and a
mutated form lacking a receptor binding motif (riL-8b) were studied initially in vitro and in vivo. |
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