Isolation and bioactivity screening of chemical constituents extracted from gracilaria changii
Gracilaria changii has been extracted and fractionated to obtain the ethanol, diethyl ether, ethyl acetate, buthanol extracts and polysaccharide. In this research, isolation and separation of chemical compounds have been carried out by various solvent and chromatographic methods. The structure of...
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my-umt-ir.-8012016-03-11T20:05:17Z Isolation and bioactivity screening of chemical constituents extracted from gracilaria changii Tee, Ching Yee Gracilaria changii has been extracted and fractionated to obtain the ethanol, diethyl ether, ethyl acetate, buthanol extracts and polysaccharide. In this research, isolation and separation of chemical compounds have been carried out by various solvent and chromatographic methods. The structure of these pure compounds have been determined by various spectroscopic methods such as infrared (IR), ultra-violet (UV), nuclear magnetic resonance (]H, l3C and 2D NMR), mass spectroscopy (MS) and by comparison with the data reported previously. The crude extracts, isolated pure compounds and synthetic compounds were subjected to the biological activities screening test such as antioxidant, antibacterial, cytotoxic assay and TLC bioautographic method for acetylcholinesterase inhibition assay. Fakulti Sains dan Teknologi 2008-12 Thesis en http://hdl.handle.net/123456789/801 http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/801/3/license.txt ecca7a0b60eabbf88d99eae3662e2d50 http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/801/1/QK%20569%20.G8%20T4%202008%20FullText.pdf ed1cf83d1dbbf526d5ab22585c1ecaec http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/801/4/QK%20569%20.G8%20T4%202008%20Abstract.pdf 698810d5ad92a01e16891418e81cfacb http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/801/5/QK%20569%20.G8%20T4%202008%20FullText.pdf.txt 9a7cb0556bcd8ebad372a3592ee330c3 http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/801/6/QK%20569%20.G8%20T4%202008%20Abstract.pdf.txt 42f1b1a4ba47a22f30c080990a2c0825 QK 569 .G8 T4 2008 Tee, Ching Yee Isolation and bioactivity screening of chemical constituents extracted from gracilaria changii Botany -- Cryptogams -- Algae Gracilariaceae |
| institution |
Universiti Malaysia Terengganu |
| collection |
UMT Repository System |
| language |
English |
| topic |
QK 569 .G8 T4 2008 QK 569 .G8 T4 2008 Isolation and bioactivity screening of chemical constituents extracted from gracilaria changii Botany -- Cryptogams -- Algae Gracilariaceae |
| spellingShingle |
QK 569 .G8 T4 2008 QK 569 .G8 T4 2008 Isolation and bioactivity screening of chemical constituents extracted from gracilaria changii Botany -- Cryptogams -- Algae Gracilariaceae Tee, Ching Yee Isolation and bioactivity screening of chemical constituents extracted from gracilaria changii |
| description |
Gracilaria changii has been extracted and fractionated to obtain the ethanol, diethyl
ether, ethyl acetate, buthanol extracts and polysaccharide. In this research, isolation
and separation of chemical compounds have been carried out by various solvent and
chromatographic methods. The structure of these pure compounds have been determined by various spectroscopic methods such as infrared (IR), ultra-violet (UV), nuclear magnetic resonance (]H, l3C and 2D NMR), mass spectroscopy (MS) and by comparison with the data reported previously. The crude extracts, isolated pure compounds and synthetic compounds were subjected to the biological activities screening test such as antioxidant, antibacterial, cytotoxic assay and TLC bioautographic method for acetylcholinesterase inhibition assay. |
| format |
Thesis |
| author |
Tee, Ching Yee |
| author_facet |
Tee, Ching Yee |
| author_sort |
Tee, Ching Yee |
| title |
Isolation and bioactivity screening of chemical constituents extracted from gracilaria changii |
| title_short |
Isolation and bioactivity screening of chemical constituents extracted from gracilaria changii |
| title_full |
Isolation and bioactivity screening of chemical constituents extracted from gracilaria changii |
| title_fullStr |
Isolation and bioactivity screening of chemical constituents extracted from gracilaria changii |
| title_full_unstemmed |
Isolation and bioactivity screening of chemical constituents extracted from gracilaria changii |
| title_sort |
isolation and bioactivity screening of chemical constituents extracted from gracilaria changii |
| granting_institution |
Fakulti Sains dan Teknologi |
| url |
http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/801/1/QK%20569%20.G8%20T4%202008%20FullText.pdf http://umt-ir.umt.edu.my:8080/jspui/bitstream/123456789/801/4/QK%20569%20.G8%20T4%202008%20Abstract.pdf |
| _version_ |
1747835879454408704 |