Production of Kojic Acid from Sago ‘Hampas’

Kojic acid is a depigmenting agent that has diverse industrial application particularly in cosmetics, food and health care industries. This research attempts to study production of kojic acid from sago ‘hampas’ via solid state fermentation (SSF) by using Aspergillus flavus Link 44-1 and Aspergillu...

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Main Author:	Spencer Empading, Alvin Miai
Format:	Thesis
Language:	English
Published:	2015
Subjects:	GE Environmental Sciences Q Science (General)
Online Access:	http://ir.unimas.my/id/eprint/10935/1/Alvin%20Miai.pdf
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id	my-unimas-ir.10935
record_format	uketd_dc
spelling	my-unimas-ir.109352023-08-01T07:40:53Z Production of Kojic Acid from Sago ‘Hampas’ 2015 Spencer Empading, Alvin Miai GE Environmental Sciences Q Science (General) Kojic acid is a depigmenting agent that has diverse industrial application particularly in cosmetics, food and health care industries. This research attempts to study production of kojic acid from sago ‘hampas’ via solid state fermentation (SSF) by using Aspergillus flavus Link 44-1 and Aspergillus flavus NSH9 as the dual strain inoculant. In the preliminary studies of kojic acid production, a maximum yield of 3.651 g/L, 3.332 g/L, and 3.999 g/L was produced via SSF using A. flavus NSH9, A. flavus Link 44-1, and A mixture of both strains respectively. Optimization of cultural conditions for kojic acid was conducted using the Response Surface Methodology (RSM). The process parameters studied were initial moisture content (50-90%, v/w), inoculum size (5-35%, v/w), urea concentration (0.5-3.5%, v/w), mineral salts solution (5-35%, v/w), and incubation time (9-21 days). Optimization of kojic acid production was successful as the yield of kojic acid obtained was higher than the predicted value in the RSM. A maximum yield of 3.102 g/L, 2.745 g/L, and 3.102 g/L was produced via SSF using A. flavus NSH9, A. flavus Link 44-1, and A mixture of both strains respectively. 2015 Thesis http://ir.unimas.my/id/eprint/10935/ http://ir.unimas.my/id/eprint/10935/1/Alvin%20Miai.pdf text en validuser masters Universiti Malaysia Sarawak, (UNIMAS) Faculty of Resources Science and Technology
institution	Universiti Malaysia Sarawak
collection	UNIMAS Institutional Repository
language	English
topic	GE Environmental Sciences Q Science (General)
spellingShingle	GE Environmental Sciences Q Science (General) Spencer Empading, Alvin Miai Production of Kojic Acid from Sago ‘Hampas’
description	Kojic acid is a depigmenting agent that has diverse industrial application particularly in cosmetics, food and health care industries. This research attempts to study production of kojic acid from sago ‘hampas’ via solid state fermentation (SSF) by using Aspergillus flavus Link 44-1 and Aspergillus flavus NSH9 as the dual strain inoculant. In the preliminary studies of kojic acid production, a maximum yield of 3.651 g/L, 3.332 g/L, and 3.999 g/L was produced via SSF using A. flavus NSH9, A. flavus Link 44-1, and A mixture of both strains respectively. Optimization of cultural conditions for kojic acid was conducted using the Response Surface Methodology (RSM). The process parameters studied were initial moisture content (50-90%, v/w), inoculum size (5-35%, v/w), urea concentration (0.5-3.5%, v/w), mineral salts solution (5-35%, v/w), and incubation time (9-21 days). Optimization of kojic acid production was successful as the yield of kojic acid obtained was higher than the predicted value in the RSM. A maximum yield of 3.102 g/L, 2.745 g/L, and 3.102 g/L was produced via SSF using A. flavus NSH9, A. flavus Link 44-1, and A mixture of both strains respectively.
format	Thesis
qualification_level	Master's degree
author	Spencer Empading, Alvin Miai
author_facet	Spencer Empading, Alvin Miai
author_sort	Spencer Empading, Alvin Miai
title	Production of Kojic Acid from Sago ‘Hampas’
title_short	Production of Kojic Acid from Sago ‘Hampas’
title_full	Production of Kojic Acid from Sago ‘Hampas’
title_fullStr	Production of Kojic Acid from Sago ‘Hampas’
title_full_unstemmed	Production of Kojic Acid from Sago ‘Hampas’
title_sort	production of kojic acid from sago ‘hampas’
granting_institution	Universiti Malaysia Sarawak, (UNIMAS)
granting_department	Faculty of Resources Science and Technology
publishDate	2015
url	http://ir.unimas.my/id/eprint/10935/1/Alvin%20Miai.pdf
_version_	1783728090455736320

Production of Kojic Acid from Sago ‘Hampas’

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