Gene expression study on tumour suppressor gene rassfi isoforms and selected inflammatory cytokines in bladder carcinoma

Bladder carcinoma (BC) arises as a result of deregulation in oncogene and tumor suppressor gene. Loss of heterozygosity at chromosome region 3p has become common in most cancer development. A tumour suppessor gene, RASSF1 located at this particular egion has been reported to be hypermethylated in mo...

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Main Author:	Nur Diana, Anuar
Format:	Thesis
Language:	English
Published:	2011
Subjects:	RB Pathology
Online Access:	http://ir.unimas.my/id/eprint/11816/1/Nur%20Diana%20Anuar%20ft.pdf
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id	my-unimas-ir.11816
record_format	uketd_dc
spelling	my-unimas-ir.118162023-05-26T07:25:13Z Gene expression study on tumour suppressor gene rassfi isoforms and selected inflammatory cytokines in bladder carcinoma 2011 Nur Diana, Anuar RB Pathology Bladder carcinoma (BC) arises as a result of deregulation in oncogene and tumor suppressor gene. Loss of heterozygosity at chromosome region 3p has become common in most cancer development. A tumour suppessor gene, RASSF1 located at this particular egion has been reported to be hypermethylated in most cancer including the bladder and has been a major targeted for tumour suppressor. However, this gene has known to have 7 alternative isoforms which might have different function in bladder tumourigenicity. In this study we aimed to explore the expression status of RASSF1 isofoms in BC biopsy as an effort to explore its role in BC progression. Universiti Malaysia Sarawak, (UNIMAS) 2011 Thesis http://ir.unimas.my/id/eprint/11816/ http://ir.unimas.my/id/eprint/11816/1/Nur%20Diana%20Anuar%20ft.pdf text en validuser masters Universiti Malaysia Sarawak, (UNIMAS) Faculty of Resource Science and Technology
institution	Universiti Malaysia Sarawak
collection	UNIMAS Institutional Repository
language	English
topic	RB Pathology
spellingShingle	RB Pathology Nur Diana, Anuar Gene expression study on tumour suppressor gene rassfi isoforms and selected inflammatory cytokines in bladder carcinoma
description	Bladder carcinoma (BC) arises as a result of deregulation in oncogene and tumor suppressor gene. Loss of heterozygosity at chromosome region 3p has become common in most cancer development. A tumour suppessor gene, RASSF1 located at this particular egion has been reported to be hypermethylated in most cancer including the bladder and has been a major targeted for tumour suppressor. However, this gene has known to have 7 alternative isoforms which might have different function in bladder tumourigenicity. In this study we aimed to explore the expression status of RASSF1 isofoms in BC biopsy as an effort to explore its role in BC progression.
format	Thesis
qualification_level	Master's degree
author	Nur Diana, Anuar
author_facet	Nur Diana, Anuar
author_sort	Nur Diana, Anuar
title	Gene expression study on tumour suppressor gene rassfi isoforms and selected inflammatory cytokines in bladder carcinoma
title_short	Gene expression study on tumour suppressor gene rassfi isoforms and selected inflammatory cytokines in bladder carcinoma
title_full	Gene expression study on tumour suppressor gene rassfi isoforms and selected inflammatory cytokines in bladder carcinoma
title_fullStr	Gene expression study on tumour suppressor gene rassfi isoforms and selected inflammatory cytokines in bladder carcinoma
title_full_unstemmed	Gene expression study on tumour suppressor gene rassfi isoforms and selected inflammatory cytokines in bladder carcinoma
title_sort	gene expression study on tumour suppressor gene rassfi isoforms and selected inflammatory cytokines in bladder carcinoma
granting_institution	Universiti Malaysia Sarawak, (UNIMAS)
granting_department	Faculty of Resource Science and Technology
publishDate	2011
url	http://ir.unimas.my/id/eprint/11816/1/Nur%20Diana%20Anuar%20ft.pdf
_version_	1783728098780381184

Gene expression study on tumour suppressor gene rassfi isoforms and selected inflammatory cytokines in bladder carcinoma

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