Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma

Nasopharyngeal Carcinoma (NPC) occurs as a consequence of multiple molecular events induced by environmental factors and Epstein-Barr virus (EBV) infections. The neoplastic processes may involve alterations of the tumor suppressor genes and oncogenes by genetic damage and interference with the norma...

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Main Author: Chua, Suk Ngo
Format: Thesis
Language:English
Published: 2011
Subjects:
Online Access:http://ir.unimas.my/id/eprint/13304/1/Chua%20Suk%20Ngo%20ft.pdf
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spelling my-unimas-ir.133042023-05-08T07:28:27Z Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma 2011 Chua, Suk Ngo RB Pathology Nasopharyngeal Carcinoma (NPC) occurs as a consequence of multiple molecular events induced by environmental factors and Epstein-Barr virus (EBV) infections. The neoplastic processes may involve alterations of the tumor suppressor genes and oncogenes by genetic damage and interference with the normal cellular functions by the EBV latent gene products. Overexpression of TNF receptor-associated factor 6 (TRAF6) has been reported to suppress orilP activity and loss of EBV from Burkitt's lymphoma cell line. The role of vigilin in cytoplasmic mRNA metabolism has been suggested whereby alterations in mRNA regulation by RNA binding protein have been reported in diverse cancer types. Universiti Malaysia Sarawak, (UNIMAS) 2011 Thesis http://ir.unimas.my/id/eprint/13304/ http://ir.unimas.my/id/eprint/13304/1/Chua%20Suk%20Ngo%20ft.pdf text en validuser masters Faculty of Resources Science & Technology Universiti Malaysia Sarawak, (UNIMAS)
institution Universiti Malaysia Sarawak
collection UNIMAS Institutional Repository
language English
topic RB Pathology
spellingShingle RB Pathology
Chua, Suk Ngo
Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma
description Nasopharyngeal Carcinoma (NPC) occurs as a consequence of multiple molecular events induced by environmental factors and Epstein-Barr virus (EBV) infections. The neoplastic processes may involve alterations of the tumor suppressor genes and oncogenes by genetic damage and interference with the normal cellular functions by the EBV latent gene products. Overexpression of TNF receptor-associated factor 6 (TRAF6) has been reported to suppress orilP activity and loss of EBV from Burkitt's lymphoma cell line. The role of vigilin in cytoplasmic mRNA metabolism has been suggested whereby alterations in mRNA regulation by RNA binding protein have been reported in diverse cancer types.
format Thesis
qualification_level Master's degree
author Chua, Suk Ngo
author_facet Chua, Suk Ngo
author_sort Chua, Suk Ngo
title Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma
title_short Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma
title_full Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma
title_fullStr Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma
title_full_unstemmed Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma
title_sort molecular study of selected differentially expressed genes in nasopharyngeal carcinoma
granting_institution Faculty of Resources Science & Technology
granting_department Universiti Malaysia Sarawak, (UNIMAS)
publishDate 2011
url http://ir.unimas.my/id/eprint/13304/1/Chua%20Suk%20Ngo%20ft.pdf
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