Characterization of an unusual adenovirus strain, Sibu 97

n adenovirus isolate, SIBU97, associated with an unexplained cluster of deaths of children with fatal acute myocardial dysfunction in Sarawak was characterized and compared with other human adenoviruses. The research is study the sequence comparisons with GenBank of portions of the SIBU97 genome tha...

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Main Author: Perera, David
Format: Thesis
Language:English
Published: 2005
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Online Access:http://ir.unimas.my/id/eprint/3835/1/David%20Perera%20ft.pdf
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spelling my-unimas-ir.38352023-06-22T09:27:00Z Characterization of an unusual adenovirus strain, Sibu 97 2005 Perera, David QR Microbiology n adenovirus isolate, SIBU97, associated with an unexplained cluster of deaths of children with fatal acute myocardial dysfunction in Sarawak was characterized and compared with other human adenoviruses. The research is study the sequence comparisons with GenBank of portions of the SIBU97 genome that include the E1, E2, and E3 transcript regions showed that it shared >94% identity to human species B adenoviruses and simian adenovirus type 21. A comparison of restriction digest profiles of SIBU97 with prototype species B adenoviruses and several European Ad21 variants revealed profiles generated with Bam H1, Sma ! and Kpn 1 that differed from the other adenoviruses but were closely related to prototype Ad21. Universiti Malaysia Sarawak, (UNIMAS) 2005 Thesis http://ir.unimas.my/id/eprint/3835/ http://ir.unimas.my/id/eprint/3835/1/David%20Perera%20ft.pdf text en validuser phd doctoral Universiti Malaysia Sarawak, (UNIMAS) Institute of Health and Community Medicine
institution Universiti Malaysia Sarawak
collection UNIMAS Institutional Repository
language English
topic QR Microbiology
spellingShingle QR Microbiology
Perera, David
Characterization of an unusual adenovirus strain, Sibu 97
description n adenovirus isolate, SIBU97, associated with an unexplained cluster of deaths of children with fatal acute myocardial dysfunction in Sarawak was characterized and compared with other human adenoviruses. The research is study the sequence comparisons with GenBank of portions of the SIBU97 genome that include the E1, E2, and E3 transcript regions showed that it shared >94% identity to human species B adenoviruses and simian adenovirus type 21. A comparison of restriction digest profiles of SIBU97 with prototype species B adenoviruses and several European Ad21 variants revealed profiles generated with Bam H1, Sma ! and Kpn 1 that differed from the other adenoviruses but were closely related to prototype Ad21.
format Thesis
qualification_name Doctor of Philosophy (PhD.)
qualification_level Doctorate
author Perera, David
author_facet Perera, David
author_sort Perera, David
title Characterization of an unusual adenovirus strain, Sibu 97
title_short Characterization of an unusual adenovirus strain, Sibu 97
title_full Characterization of an unusual adenovirus strain, Sibu 97
title_fullStr Characterization of an unusual adenovirus strain, Sibu 97
title_full_unstemmed Characterization of an unusual adenovirus strain, Sibu 97
title_sort characterization of an unusual adenovirus strain, sibu 97
granting_institution Universiti Malaysia Sarawak, (UNIMAS)
granting_department Institute of Health and Community Medicine
publishDate 2005
url http://ir.unimas.my/id/eprint/3835/1/David%20Perera%20ft.pdf
_version_ 1783727969947090944