Chemical Constituents of Calophyllum Inophyllum and Cratoxylum Glaucum (Guttiferae)

Extensive studies on the plants, Calophyllum inophyllum and Cratoxylum glaucum have resulted in the isolation of ten compounds. All these compounds were isolated by means of chromatographic methods and their structures derived on the basis of spectroscopic evidence, mainly 1D and 2D nuclear magne...

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Main Author:	Kua, Audrey Siew May
Format:	Thesis
Language:	English English
Published:	2006
Subjects:	Calophyllum inophyllum Guttiferae
Online Access:	http://psasir.upm.edu.my/id/eprint/109/1/549072_t_fs_2006_3.pdf
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id	my-upm-ir.109
record_format	uketd_dc
spelling	my-upm-ir.1092013-05-27T06:45:37Z Chemical Constituents of Calophyllum Inophyllum and Cratoxylum Glaucum (Guttiferae) 2006-01 Kua, Audrey Siew May Extensive studies on the plants, Calophyllum inophyllum and Cratoxylum glaucum have resulted in the isolation of ten compounds. All these compounds were isolated by means of chromatographic methods and their structures derived on the basis of spectroscopic evidence, mainly 1D and 2D nuclear magnetic resonance spectroscopy. Chemical investigations on the root bark extracts of Calophyllum inophyllum has yielded two new xanthones, inophyllin A and inophyllin B, three known xanthones, brasilixanthone B, tovopyrifolin C, caloxanthone B, one triterpene, friedelin and one triterpenoid, -sitosterol. Cratoxylum glaucum afforded two triterpenes, friedelin and stigmasterol, two known anthraquinones, 1,8-dihydroxy-3-methoxy-6-methylanthraquinone and vismiaquinone and a known xanthone, dimethylmangostin. Cytotoxic assay was performed using CEM-SS Cell Line. All the crude extracts of Calophyllum inophyllum and Cratoxylum glaucum showed no activity. Antimicrobial assay was carried out towards four pathogenic bacteria, Methicillin Resistant Staphylococcus aures, Pseudomonas aeruginosa, Staphylococcus typhimurium and Bacillus subtilis. Most of the crude extracts tested against these microbes gave no activity. Larvicidal test was carried out towards the larvae of Aedes aegypti. The larvae were not susceptible to all of the crude extracts and pure compounds of Calophyllum inophyllum and Cratoxylum glaucum Calophyllum inophyllum Guttiferae 2006-01 Thesis http://psasir.upm.edu.my/id/eprint/109/ http://psasir.upm.edu.my/id/eprint/109/1/549072_t_fs_2006_3.pdf application/pdf en public masters Universiti Putra Malaysia Calophyllum inophyllum Guttiferae Faculty of Science English
institution	Universiti Putra Malaysia
collection	PSAS Institutional Repository
language	English English
topic	Calophyllum inophyllum Guttiferae
spellingShingle	Calophyllum inophyllum Guttiferae Kua, Audrey Siew May Chemical Constituents of Calophyllum Inophyllum and Cratoxylum Glaucum (Guttiferae)
description	Extensive studies on the plants, Calophyllum inophyllum and Cratoxylum glaucum have resulted in the isolation of ten compounds. All these compounds were isolated by means of chromatographic methods and their structures derived on the basis of spectroscopic evidence, mainly 1D and 2D nuclear magnetic resonance spectroscopy. Chemical investigations on the root bark extracts of Calophyllum inophyllum has yielded two new xanthones, inophyllin A and inophyllin B, three known xanthones, brasilixanthone B, tovopyrifolin C, caloxanthone B, one triterpene, friedelin and one triterpenoid, -sitosterol. Cratoxylum glaucum afforded two triterpenes, friedelin and stigmasterol, two known anthraquinones, 1,8-dihydroxy-3-methoxy-6-methylanthraquinone and vismiaquinone and a known xanthone, dimethylmangostin. Cytotoxic assay was performed using CEM-SS Cell Line. All the crude extracts of Calophyllum inophyllum and Cratoxylum glaucum showed no activity. Antimicrobial assay was carried out towards four pathogenic bacteria, Methicillin Resistant Staphylococcus aures, Pseudomonas aeruginosa, Staphylococcus typhimurium and Bacillus subtilis. Most of the crude extracts tested against these microbes gave no activity. Larvicidal test was carried out towards the larvae of Aedes aegypti. The larvae were not susceptible to all of the crude extracts and pure compounds of Calophyllum inophyllum and Cratoxylum glaucum
format	Thesis
qualification_level	Master's degree
author	Kua, Audrey Siew May
author_facet	Kua, Audrey Siew May
author_sort	Kua, Audrey Siew May
title	Chemical Constituents of Calophyllum Inophyllum and Cratoxylum Glaucum (Guttiferae)
title_short	Chemical Constituents of Calophyllum Inophyllum and Cratoxylum Glaucum (Guttiferae)
title_full	Chemical Constituents of Calophyllum Inophyllum and Cratoxylum Glaucum (Guttiferae)
title_fullStr	Chemical Constituents of Calophyllum Inophyllum and Cratoxylum Glaucum (Guttiferae)
title_full_unstemmed	Chemical Constituents of Calophyllum Inophyllum and Cratoxylum Glaucum (Guttiferae)
title_sort	chemical constituents of calophyllum inophyllum and cratoxylum glaucum (guttiferae)
granting_institution	Universiti Putra Malaysia
granting_department	Faculty of Science
publishDate	2006
url	http://psasir.upm.edu.my/id/eprint/109/1/549072_t_fs_2006_3.pdf
_version_	1747810139295973376

Chemical Constituents of Calophyllum Inophyllum and Cratoxylum Glaucum (Guttiferae)

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