Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus
The aim of the research is to develop an effective vaccine against vibriosis. Vibriosis is a bacterial disease caused by Vibrio spp due to the intensive production activity of brackishwater ponds and cage-cultured fish. The pathogenicity study of V alginolyticus was performed by challenging the j...
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| Language: | English English |
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2000
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| Online Access: | http://psasir.upm.edu.my/id/eprint/11211/1/FPSK_M_2001_1_A.pdf |
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my-upm-ir.112112011-08-08T05:08:53Z Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus 2000-08 Mohd Taib, Nor Azizah The aim of the research is to develop an effective vaccine against vibriosis. Vibriosis is a bacterial disease caused by Vibrio spp due to the intensive production activity of brackishwater ponds and cage-cultured fish. The pathogenicity study of V alginolyticus was performed by challenging the juvenile seabass (10±0.75 g) with 5 different isolates of V alginolyticus at different cell concentrations. All the isolates caused mortality to fish at a concentration as low as 0.2 optical density (6.28 X 103 CFU/ml). Ultrastructure changes observed by scanning and transmission electron microscopy, revealed the presence of V .alginolyticus in the gills, liver, muscle, spleen and kidney of infected fish. In addition, the V .alginolyticus cells were observed in the spleen. These pathological changes showed that V alginolyticus was responsible for the death of the infected seabass. 2000-08 Thesis http://psasir.upm.edu.my/id/eprint/11211/ http://psasir.upm.edu.my/id/eprint/11211/1/FPSK_M_2001_1_A.pdf application/pdf en public masters Universiti Putra Malaysia Faculty of Medicine and Health Science English |
| institution |
Universiti Putra Malaysia |
| collection |
PSAS Institutional Repository |
| language |
English English |
| topic |
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| spellingShingle |
Mohd Taib, Nor Azizah Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus |
| description |
The aim of the research is to develop an effective vaccine against vibriosis.
Vibriosis is a bacterial disease caused by Vibrio spp due to the intensive
production activity of brackishwater ponds and cage-cultured fish. The
pathogenicity study of V alginolyticus was performed by challenging the juvenile
seabass (10±0.75 g) with 5 different isolates of V alginolyticus at different cell
concentrations. All the isolates caused mortality to fish at a concentration as low
as 0.2 optical density (6.28 X 103 CFU/ml). Ultrastructure changes observed by
scanning and transmission electron microscopy, revealed the presence of
V .alginolyticus in the gills, liver, muscle, spleen and kidney of infected fish. In
addition, the V .alginolyticus cells were observed in the spleen. These
pathological changes showed that V alginolyticus was responsible for the death of
the infected seabass. |
| format |
Thesis |
| qualification_level |
Master's degree |
| author |
Mohd Taib, Nor Azizah |
| author_facet |
Mohd Taib, Nor Azizah |
| author_sort |
Mohd Taib, Nor Azizah |
| title |
Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus
|
| title_short |
Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus
|
| title_full |
Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus
|
| title_fullStr |
Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus
|
| title_full_unstemmed |
Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus
|
| title_sort |
vibriosis vaccine development: pathogenesis, immunological and molecular characterization of vibrio alginolyticus |
| granting_institution |
Universiti Putra Malaysia |
| granting_department |
Faculty of Medicine and Health Science |
| publishDate |
2000 |
| url |
http://psasir.upm.edu.my/id/eprint/11211/1/FPSK_M_2001_1_A.pdf |
| _version_ |
1747811222888120320 |