Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria

Type 2 diabetes mellitus is the predominant type of diabetes mellitus and the type likely to go undiagnosed. Oxidative damage was suggested in the development of diabetic microangiopathic and macroangiopathic complications in these patients. Since the long-term complications are the main cause o...

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Main Author:	Sim, Sze Kiat
Format:	Thesis
Language:	English English
Published:	2001
Subjects:
Online Access:	http://psasir.upm.edu.my/id/eprint/11220/1/FPSK_M_2001_8_.pdf
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id	my-upm-ir.11220
record_format	uketd_dc
spelling	my-upm-ir.112202024-06-12T08:06:53Z Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria 2001-06 Sim, Sze Kiat Type 2 diabetes mellitus is the predominant type of diabetes mellitus and the type likely to go undiagnosed. Oxidative damage was suggested in the development of diabetic microangiopathic and macroangiopathic complications in these patients. Since the long-term complications are the main cause of morbidity and mortality in diabetic patients, a quantitative determination of the level of oxidative stress is a valuable indicator of the degree of the severity of the disease and of the effectiveness of treatment. The main aim of this study is to evaluate the extent of oxidative DNA damage with different severity of microalbuminuria in diabetic patients and its associations with other metabolic controls. The comet assay was adopted to measure the level of oxidative DNA damage in leukocytes. One hundred and twenty seven (127) Type 2 diabetic patients with- and without microalbuminuria were recruited from the Outpatients Department and 2001-06 Thesis http://psasir.upm.edu.my/id/eprint/11220/ http://psasir.upm.edu.my/id/eprint/11220/1/FPSK_M_2001_8_.pdf text en public masters Universiti Putra Malaysia Faculty of Medicine and Health Science Hambali, Zarida English
institution	Universiti Putra Malaysia
collection	PSAS Institutional Repository
language	English English
advisor	Hambali, Zarida
topic
spellingShingle	Sim, Sze Kiat Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria
description	Type 2 diabetes mellitus is the predominant type of diabetes mellitus and the type likely to go undiagnosed. Oxidative damage was suggested in the development of diabetic microangiopathic and macroangiopathic complications in these patients. Since the long-term complications are the main cause of morbidity and mortality in diabetic patients, a quantitative determination of the level of oxidative stress is a valuable indicator of the degree of the severity of the disease and of the effectiveness of treatment. The main aim of this study is to evaluate the extent of oxidative DNA damage with different severity of microalbuminuria in diabetic patients and its associations with other metabolic controls. The comet assay was adopted to measure the level of oxidative DNA damage in leukocytes. One hundred and twenty seven (127) Type 2 diabetic patients with- and without microalbuminuria were recruited from the Outpatients Department and
format	Thesis
qualification_level	Master's degree
author	Sim, Sze Kiat
author_facet	Sim, Sze Kiat
author_sort	Sim, Sze Kiat
title	Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria
title_short	Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria
title_full	Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria
title_fullStr	Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria
title_full_unstemmed	Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria
title_sort	oxidative dna damage in leukocytes and its association with metabolic control in diabetic patients with and without microalbuminuria
granting_institution	Universiti Putra Malaysia
granting_department	Faculty of Medicine and Health Science
publishDate	2001
url	http://psasir.upm.edu.my/id/eprint/11220/1/FPSK_M_2001_8_.pdf
_version_	1804888626877693952

Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria

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