Effects Of Andrographis Paniculata, Carica Papaya And Cassia Alata Extracts On The Reproductive Systems Of Mice
In facing the high rise of population especially in developing countries, a continuing need is felt for oral and non-surgical methods of contraception. Plants extracts have been used widely in traditional medical practice especially as an anti-fertility agent. The Andrographis paniculata, Cassia...
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| Main Author: | |
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| Format: | Thesis |
| Language: | English English |
| Published: |
2003
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| Subjects: | |
| Online Access: | http://psasir.upm.edu.my/id/eprint/11250/1/FPSK_M_2003_7.pdf |
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| Summary: | In facing the high rise of population especially in developing countries, a continuing
need is felt for oral and non-surgical methods of contraception. Plants extracts have been
used widely in traditional medical practice especially as an anti-fertility agent. The
Andrographis paniculata, Cassia alata and Carica papaya extracts have been reported
to poses multifunctional properties. In the present studies, the effects of 20 mg/kg body
weight ethanol extract of Andrographis paniculata, Carica papaya and Cassia alata on
the reproductive systems was studied after 30 days and 90 days of treatment in female
and male mice. Clomiphene citrate, given daily at 50 mglkg body weight, was used for
the purposed comparison. Results obtained showed that the female genital organs
(ovaries and uteri) weight was reduced significantly after treatment with Carica papaya
and Andrographis paniculata respectiVely. All females groups showed changes in
fertility and reduction in litter number. |
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