Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma

Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is an extremely difficult disease to manage and one of the ten most common cancers in Malaysia. However, the molecular mechanisms that contribute to tumour progression in hepatocarcinogenesis remain unknown. In recent years, the evidence that the Wnt signaling pathw...

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Main Author: Ban, Kechen
Format: Thesis
Language:English
English
Published: 2002
Subjects:
Online Access:http://psasir.upm.edu.my/id/eprint/11271/1/FPSK_P_2002_1.pdf
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id my-upm-ir.11271
record_format uketd_dc
spelling my-upm-ir.112712024-06-13T07:11:31Z Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma 2002-10 Ban, Kechen Hepatocellular carcinoma (HCC) is an extremely difficult disease to manage and one of the ten most common cancers in Malaysia. However, the molecular mechanisms that contribute to tumour progression in hepatocarcinogenesis remain unknown. In recent years, the evidence that the Wnt signaling pathway may play a crucial role in the hepatocarcinogenesis represents a major breakthrough. Despite efforts made in this area of research, the relationship between the related genes of Wnt signaling pathway is still far from comprehensive. By employing immunohistochemistry and DNA sequencing, some related proteins and genes of the Wnt signaling pathway were investigated in 23 paired HCC and adjacent liver specimens from a tertiary referral centre in Malaysia. 2002-10 Thesis http://psasir.upm.edu.my/id/eprint/11271/ http://psasir.upm.edu.my/id/eprint/11271/1/FPSK_P_2002_1.pdf text en public doctoral Universiti Putra Malaysia Faculty of Medicine and Health Science Seow, Heng Fong English
institution Universiti Putra Malaysia
collection PSAS Institutional Repository
language English
English
advisor Seow, Heng Fong
topic


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Ban, Kechen
Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma
description Hepatocellular carcinoma (HCC) is an extremely difficult disease to manage and one of the ten most common cancers in Malaysia. However, the molecular mechanisms that contribute to tumour progression in hepatocarcinogenesis remain unknown. In recent years, the evidence that the Wnt signaling pathway may play a crucial role in the hepatocarcinogenesis represents a major breakthrough. Despite efforts made in this area of research, the relationship between the related genes of Wnt signaling pathway is still far from comprehensive. By employing immunohistochemistry and DNA sequencing, some related proteins and genes of the Wnt signaling pathway were investigated in 23 paired HCC and adjacent liver specimens from a tertiary referral centre in Malaysia.
format Thesis
qualification_level Doctorate
author Ban, Kechen
author_facet Ban, Kechen
author_sort Ban, Kechen
title Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma
title_short Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma
title_full Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma
title_fullStr Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma
title_full_unstemmed Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma
title_sort wnt signaling pathway related genes in hepatocellular carcinoma
granting_institution Universiti Putra Malaysia
granting_department Faculty of Medicine and Health Science
publishDate 2002
url http://psasir.upm.edu.my/id/eprint/11271/1/FPSK_P_2002_1.pdf
_version_ 1804888634664419328

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