Antitumour Promoting Activity And Mode Of Action Of Methanolic Extracts Of Selected Malaysian Seaweeds And Oil Palm Fronds
Dietary and non dietary biophenols may potentially be chemoprotective against various cancers. This research aims to investigate the cancer preventive and tumoricidal properties of selected Malaysian seaweeds and oil palm leaves as a source of phenolic compounds. Initially, the anti-proliferatio...
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2009
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my-upm-ir.120612013-05-27T07:50:57Z Antitumour Promoting Activity And Mode Of Action Of Methanolic Extracts Of Selected Malaysian Seaweeds And Oil Palm Fronds 2009-10 Namvar, Farideh Dietary and non dietary biophenols may potentially be chemoprotective against various cancers. This research aims to investigate the cancer preventive and tumoricidal properties of selected Malaysian seaweeds and oil palm leaves as a source of phenolic compounds. Initially, the anti-proliferation activities of, red (Eucheuma cottonii), green (Caulerpa lentillifera) and brown (Sargassum polycystum) seaweeds methanolic extract, against five important human cancer cell lines MCF-7, (human breast carcinoma cell line, estrogen positive) MDA-MB-231, (human breast carcinoma cell line, estrogen negative) HeLa, (human cervical adenocarcinoma cell line) HepG2, (human hepatocellular carcinoma cell line) HT-29, (human colon carcinoma) and normal Vero (African green monkey kidney cell line) were assessed. The MTT assays indicated that the 3 seaweeds extracts were cytotoxic against all these cancer cell lines in a dose-dependent manner,with Eucheuma cottonii having the greatest inhibition activity. Algae - Malaysia Oil palm - Malaysia Cancer - Prevention 2009-10 Thesis http://psasir.upm.edu.my/id/eprint/12061/ http://psasir.upm.edu.my/id/eprint/12061/1/IB_2009_18_A.pdf application/pdf en public phd doctoral Universiti Putra Malaysia Algae - Malaysia Oil palm - Malaysia Cancer - Prevention Institute of Bioscience English |
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Universiti Putra Malaysia |
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PSAS Institutional Repository |
| language |
English English |
| topic |
Algae - Malaysia Oil palm - Malaysia Cancer - Prevention |
| spellingShingle |
Algae - Malaysia Oil palm - Malaysia Cancer - Prevention Namvar, Farideh Antitumour Promoting Activity And Mode Of Action Of Methanolic Extracts Of Selected Malaysian Seaweeds And Oil Palm Fronds |
| description |
Dietary and non dietary biophenols may potentially be chemoprotective against various
cancers. This research aims to investigate the cancer preventive and tumoricidal
properties of selected Malaysian seaweeds and oil palm leaves as a source of phenolic
compounds.
Initially, the anti-proliferation activities of, red (Eucheuma cottonii), green (Caulerpa
lentillifera) and brown (Sargassum polycystum) seaweeds methanolic extract, against
five important human cancer cell lines MCF-7, (human breast carcinoma cell line,
estrogen positive) MDA-MB-231, (human breast carcinoma cell line, estrogen negative)
HeLa, (human cervical adenocarcinoma cell line) HepG2, (human hepatocellular
carcinoma cell line) HT-29, (human colon carcinoma) and normal Vero (African green
monkey kidney cell line) were assessed. The MTT assays indicated that the 3 seaweeds
extracts were cytotoxic against all these cancer cell lines in a dose-dependent manner,with Eucheuma cottonii having the greatest inhibition activity. |
| format |
Thesis |
| qualification_name |
Doctor of Philosophy (PhD.) |
| qualification_level |
Doctorate |
| author |
Namvar, Farideh |
| author_facet |
Namvar, Farideh |
| author_sort |
Namvar, Farideh |
| title |
Antitumour Promoting Activity And Mode Of Action Of
Methanolic Extracts Of Selected Malaysian Seaweeds
And Oil Palm Fronds
|
| title_short |
Antitumour Promoting Activity And Mode Of Action Of
Methanolic Extracts Of Selected Malaysian Seaweeds
And Oil Palm Fronds
|
| title_full |
Antitumour Promoting Activity And Mode Of Action Of
Methanolic Extracts Of Selected Malaysian Seaweeds
And Oil Palm Fronds
|
| title_fullStr |
Antitumour Promoting Activity And Mode Of Action Of
Methanolic Extracts Of Selected Malaysian Seaweeds
And Oil Palm Fronds
|
| title_full_unstemmed |
Antitumour Promoting Activity And Mode Of Action Of
Methanolic Extracts Of Selected Malaysian Seaweeds
And Oil Palm Fronds
|
| title_sort |
antitumour promoting activity and mode of action of
methanolic extracts of selected malaysian seaweeds
and oil palm fronds |
| granting_institution |
Universiti Putra Malaysia |
| granting_department |
Institute of Bioscience |
| publishDate |
2009 |
| url |
http://psasir.upm.edu.my/id/eprint/12061/1/IB_2009_18_A.pdf |
| _version_ |
1747811296903954432 |