Effects of bortezomib on HIF-1 and HIF-2 transcriptional activities

Effects of bortezomib on HIF-1 and HIF-2 transcriptional activities

Bortezomib is the first proteasomal inhibitor (PI) to be used therapeutically in humans for treating relapse cases of multiple myeloma and mantle cell lymphoma. A proposed mechanism is that it prevents proteasomal degradation of pro-apoptotic proteins, leading to enhance apoptosis. Although the alp...

Saved in:

书目详细资料
主要作者:	Abd Aziz, Noraini
格式:	Thesis
语言:	English
出版:	2013
主题:	Protease inhibitors - Therapeutic use Cancer - Chemotherapy
在线阅读:	http://psasir.upm.edu.my/id/eprint/48690/1/FBSB%202013%2039R.pdf
标签:	添加标签没有标签, 成为第一个标记此记录!

相似书籍

Design and synthesis of a potential inhibitor for DEN2 NS2B/NS3 serine protease /
由: Lee, Yean Kee
出版: (2011)

Development of protease deficient Meyerozyma guilliermondii strain so for overexpression of thermostable T1 lipase
由: Lorrine, Okojie Eseoghene
出版: (2022)

Molecular cloning, functional assessment and transcriptome characterization of cysteine protease inhibitor and kunitz trypsin inhibitor from turmeric (Curcuma longa L.)
由: Chan, Seow Neng
出版: (2016)

Molecular expression, characterization and potential applications of a thermostable alkaline protease from Geobacillus thermoglucosidasius SKF4
由: Dan, Allison Suleiman
出版: (2022)

Establishment of cell-based assay for measuring Hypoxia-inducible factor (HIF) transcriptional activities
由: Cheow, Pheik Sheen
出版: (2017)

Screening and partial purification of protease inhibitors from Senna surattensis leaves /
由: Ahmad Firdhaus Arham
出版: (2011)

Molecular interaction analyses of selected drugs as dengue virus type-2 protease inhibitors /
由: Rufaidah Othman
出版: (2017)

Cathepsin D expression in hydatidiform mole /
由: Suryani Md. Jusoh@Mohd Yusoff
出版: (2000)

Anti-cancer effects of 1'S-1'-Acetoxychavicol acetate and its hemi-synthetic analogues on cancer cell lines /
由: Liew, Su Ki
出版: (2018)

Phytochemical studies and bioactivity evaluation (DENV-2 NS2B/NS3) of Beilschmiedia glabra and Endiandra kingiana (Lauraceae) /
由: Syazreen Nadia Sulaiman
出版: (2019)

Evaluation of Cryptolepis Sanguinolenta (CSE) and Paclitaxel in combination as a potent chemotherapeutic option /
由: Farina Muhamad
出版: (2007)

In vitro treatment of MCF-7 and MDA-MB-231 breast cancer cell lines with doxorubicin and vincristine sulphate calcium carbonate nanoparticles
由: Mengyi, Xue
出版: (2019)

Mixed oleic acid stealth liposomes for anticancer drugs delivery /
由: Vicit Rizal Eh Suk
出版: (2018)

Preliminary assessment of the effect of plant protease inhibitors on the expression of heterologous genes in plant cells /
由: Khalighi, Nassim
出版: (2011)

In-vitro comparison of anticancer activity between pure gallic acid and gallic acid - iron oxide coated with polyethylene glycol nanoparticles
由: Rosman, Raihana
出版: (2018)

Sensitization of human colon adenocarcinoma cells to chlorambuchil by plant polyphenols /
由: Zhang, Kai
出版: (1996)

The role of HIF-1α and VGSCs in influencing metastasis of breast cancer cells
由: Dewadas, Hemaniswarri Dewi
出版: (2018)

Screening and isolation of protease inhibitors from cassia fistula's fruit /
由: Kamarul Huda Kamaruddin
出版: (2011)

Search of dengue protease inhibitors from natural product database using ensemble-based virtual screening /
由: Nor Farrah Wahidah Ridzwan
出版: (2018)

Computational approach to drug discovery : search for photodynamic therapy agents against cancer and inhibitors of dengue NS2B/NS3 serine protease /
由: Frimayanti, Neni
出版: (2012)

Chemotherapeutics potential of matcha green tea(Camellia sinensis (L.) Kuntze) on weri-Rb-1 retinoblastoma cancer cells
由: Sayuti, Nor Hafiza
出版: (2022)

Spectroscopic and molecular modeling studies on the interaction of Tyrosine Kinase inhibitors with human serum albumin /
由: Kabir Md. Zahirul
出版: (2018)

Studies on the effects of flavonoids and related natural products on hyaluronidase and cyclic AMP phosphodiesterase enzymes /
由: Kuppusamy, Umah Rani
出版: (1993)

Screening and purification of protease inhibitors from Mimosa Diplotricha leaves /
由: Nora Asyikin Ramli
出版: (2011)

Partial purification and characterization of protease inhibitors from acalypha wilkesiana leaves /
由: Rabiatul Adawiyah Mohd Hairuni
出版: (2011)

Computational design strategy of pharmaceutical co-crystals : a case study of anti-cancer drugs /
由: Nadia Hanim Sabri
出版: (2018)

Gene polymorphisms of angiotensin-converting enzyme, angiotensin type 1 receptor and ⁪⁯α-adducin associated with renin angiotensin-aldosterone system in Malaysian end-stage renal disease patients
由: Ali, Aisyah
出版: (2012)

Nigella sativa and its derivative thymoquinone ameliorates the negative impact of cyclophosphamide on mouse male germ cells and embryo /
由: Nadia Hanis Abdul Samat
出版: (2020)

Synthesis And Characterization Of Potential Human Hypoxia Inducible Factor (Hif) Prolyl Hydroxylase Domain 2 (Phd-2) Inhibitors
由: Toh, Lee Roy
出版: (2021)

Inhibitory potential of Azadirchta indica-enriched yogurt against key enzymes linked to type-2 diabetes and hypertension /
由: Shori, Amal Bakr
出版: (2009)

Evaluation of curcumin derivatives as new cyclooxygenase-2 inhibitors via in silico and in vitro analyses
由: Abdul Bahari, Mohammad Nazri
出版: (2016)

Synthesis of chalcone-based six and seven membered heterocyclic compounds and their biological activities against H1N1 virus /
由: Yaeghoobi, Marzieh
出版: (2012)

Hybrid optimal control-swarm intelligence for optimization of selected cancer chemotherapy model /
由: Shindi, Omar Ali Mohammad
出版: (2018)

The effect of valsartan and enalapril on the male spontaneously hypertensive rats sexual activity /
由: Norhasanin bin Ahmad
出版: (2005)

Synthesis of potential antitumour compounds as selective ligands for antiestrogen-binding sites /
由: Srikanth, Natarajan
出版: (1995)

Characterization, histological evaluation and efficacy of docetaxel-loaded cockle shellderived CaCO3 nanoparticles in vitro and in vivo
由: Hammadi, Nahidah Ibrahim
出版: (2018)

Apoptotic effects and chemical investigation of active extracts of Curcuma mangga rhizomes /
由: Hong, Gin Wah
出版: (2018)

Design, Synthesis And Characterization Of 4-Oxobutanoic Acid Analogues As Potential Human Hypoxia Inducible Factor (Hif) Prolyl Hydroxylase Domain 2 (Phd-2) Inhibitors
由: Chong, Mui Phin
出版: (2018)

Chemopreventive and chemotherapeutic activities of Dracaena Cinnabari Balf.f against oral cancer in Vivo /
由: Al-Afifi, Nashwan Abdullah Abdo
出版: (2018)

Antioxidant and cytotoxicity activities of veitchia merrillii fruits /
由: Vafaei, Ali
出版: (2013)

Services hosted by the Perpustakaan Sultan Abdul Samad, Universiti Putra Malaysia with Cooperation MySyL Group