Effects of bortezomib on HIF-1 and HIF-2 transcriptional activities
Bortezomib is the first proteasomal inhibitor (PI) to be used therapeutically in humans for treating relapse cases of multiple myeloma and mantle cell lymphoma. A proposed mechanism is that it prevents proteasomal degradation of pro-apoptotic proteins, leading to enhance apoptosis. Although the alp...
Saved in:
主要作者: | |
---|---|
格式: | Thesis |
语言: | English |
出版: |
2013
|
主题: | |
在线阅读: | http://psasir.upm.edu.my/id/eprint/48690/1/FBSB%202013%2039R.pdf |
标签: |
添加标签
没有标签, 成为第一个标记此记录!
|