Characterisation and dissolution kinetics of tamarind and pineapple tablets

Fruits in fresh form have limited shelf life and often face difficulty during handling and preparation therefore tabletting is one of the best alternative for the fruit juice. This research done due to the lack of research in the area of tamarind and pineapple tablet characterisation and dissolution...

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Main Author: Mokhtar, Taufiq Aminullah
Format: Thesis
Language:English
Published: 2015
Subjects:
Online Access:http://psasir.upm.edu.my/id/eprint/57556/1/FK%202015%2064RR.pdf
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spelling my-upm-ir.575562017-09-28T09:58:41Z Characterisation and dissolution kinetics of tamarind and pineapple tablets 2015-07 Mokhtar, Taufiq Aminullah Fruits in fresh form have limited shelf life and often face difficulty during handling and preparation therefore tabletting is one of the best alternative for the fruit juice. This research done due to the lack of research in the area of tamarind and pineapple tablet characterisation and dissolution kinetics. Its dissolution properties are important as it depends on the process of tablets dissolve in distill water, simulated gastric juice of pH1.2 and simulated intestinal juice of pH 6.8 which has been used in this study. Both of the fruits went spray drying process. The powders were then compressed into tablets using a cylindrical uniaxial die. Pressures of up to 22.28 MPa were applied to the die via a universal testing machine. The nutritional value in terms of crude protein (0.33% - 0.60%), moisture content (4.8% - 25.31%), crude fiber (16.92% - 79.92%), and fat (0.40% - 0.63%) for both fruits pulp and powders showed significant differences in values with p<0.05. The vitamin C release was analyzed using 2,4-dinitrophenyl hydrazine (DNPH) method. In-vitro dissolution study of the fruit tablet were been analysed by four established release kinetics model equations. The best fit mathematical model for the tamarind and pineapple fruit tablets were determined based on the coefficient of correlation ‘R2’ values. A microbial stability test was done to calculate the colony forming units (CFU/g) of both tamarind and pineapple fruit powder tablets. The shelf life of pineapple tablet is 14 days and tamarind tablet is 21 days, which were in the acceptable value range of colonies for fruits as it were less than 10000 CFU/ml following the United States Food and Drug Administration (FDA). These findings indicate that it is important to compact fruit powder into tablet because fruit powder in tablet form is easy to dissolve and may provide an excellent alternative for healthy beverage consumption and a creative product development and as an approach to meet consumer’s demand. Fruit Analysis Preservation 2015-07 Thesis http://psasir.upm.edu.my/id/eprint/57556/ http://psasir.upm.edu.my/id/eprint/57556/1/FK%202015%2064RR.pdf application/pdf en public masters Universiti Putra Malaysia Fruit Analysis Preservation
institution Universiti Putra Malaysia
collection PSAS Institutional Repository
language English
topic Fruit
Analysis
Preservation
spellingShingle Fruit
Analysis
Preservation
Mokhtar, Taufiq Aminullah
Characterisation and dissolution kinetics of tamarind and pineapple tablets
description Fruits in fresh form have limited shelf life and often face difficulty during handling and preparation therefore tabletting is one of the best alternative for the fruit juice. This research done due to the lack of research in the area of tamarind and pineapple tablet characterisation and dissolution kinetics. Its dissolution properties are important as it depends on the process of tablets dissolve in distill water, simulated gastric juice of pH1.2 and simulated intestinal juice of pH 6.8 which has been used in this study. Both of the fruits went spray drying process. The powders were then compressed into tablets using a cylindrical uniaxial die. Pressures of up to 22.28 MPa were applied to the die via a universal testing machine. The nutritional value in terms of crude protein (0.33% - 0.60%), moisture content (4.8% - 25.31%), crude fiber (16.92% - 79.92%), and fat (0.40% - 0.63%) for both fruits pulp and powders showed significant differences in values with p<0.05. The vitamin C release was analyzed using 2,4-dinitrophenyl hydrazine (DNPH) method. In-vitro dissolution study of the fruit tablet were been analysed by four established release kinetics model equations. The best fit mathematical model for the tamarind and pineapple fruit tablets were determined based on the coefficient of correlation ‘R2’ values. A microbial stability test was done to calculate the colony forming units (CFU/g) of both tamarind and pineapple fruit powder tablets. The shelf life of pineapple tablet is 14 days and tamarind tablet is 21 days, which were in the acceptable value range of colonies for fruits as it were less than 10000 CFU/ml following the United States Food and Drug Administration (FDA). These findings indicate that it is important to compact fruit powder into tablet because fruit powder in tablet form is easy to dissolve and may provide an excellent alternative for healthy beverage consumption and a creative product development and as an approach to meet consumer’s demand.
format Thesis
qualification_level Master's degree
author Mokhtar, Taufiq Aminullah
author_facet Mokhtar, Taufiq Aminullah
author_sort Mokhtar, Taufiq Aminullah
title Characterisation and dissolution kinetics of tamarind and pineapple tablets
title_short Characterisation and dissolution kinetics of tamarind and pineapple tablets
title_full Characterisation and dissolution kinetics of tamarind and pineapple tablets
title_fullStr Characterisation and dissolution kinetics of tamarind and pineapple tablets
title_full_unstemmed Characterisation and dissolution kinetics of tamarind and pineapple tablets
title_sort characterisation and dissolution kinetics of tamarind and pineapple tablets
granting_institution Universiti Putra Malaysia
publishDate 2015
url http://psasir.upm.edu.my/id/eprint/57556/1/FK%202015%2064RR.pdf
_version_ 1747812178549800960